ID   A0A1Z5TV26_HORWE        Unreviewed;       358 AA.
AC   A0A1Z5TV26;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   28-JUN-2023, entry version 16.
DE   SubName: Full=Cyanide hydratase {ECO:0000313|EMBL:OTA39887.1};
GN   ORFNames=BTJ68_00251 {ECO:0000313|EMBL:OTA39887.1};
OS   Hortaea werneckii EXF-2000.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX   NCBI_TaxID=1157616 {ECO:0000313|EMBL:OTA39887.1, ECO:0000313|Proteomes:UP000194280};
RN   [1] {ECO:0000313|EMBL:OTA39887.1, ECO:0000313|Proteomes:UP000194280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-2000 {ECO:0000313|EMBL:OTA39887.1,
RC   ECO:0000313|Proteomes:UP000194280};
RA   Sinha S., Flibotte S., Neira M., Lenassi M., Gostincar C., Stajich J.E.,
RA   Nislow C.E.;
RT   "The recent genome duplication of the halophilic yeast Hortaea werneckii:
RT   insights from long-read sequencing.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC       Nitrilase family. {ECO:0000256|ARBA:ARBA00008129}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTA39887.1}.
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DR   EMBL; MUNK01000001; OTA39887.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z5TV26; -.
DR   STRING; 1157616.A0A1Z5TV26; -.
DR   VEuPathDB; FungiDB:BTJ68_00251; -.
DR   InParanoid; A0A1Z5TV26; -.
DR   OrthoDB; 2785533at2759; -.
DR   Proteomes; UP000194280; Unassembled WGS sequence.
DR   GO; GO:0000257; F:nitrilase activity; IEA:UniProt.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   CDD; cd07564; nitrilases_CHs; 1.
DR   Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR   InterPro; IPR003010; C-N_Hydrolase.
DR   InterPro; IPR036526; C-N_Hydrolase_sf.
DR   InterPro; IPR000132; Nitrilase/CN_hydratase_CS.
DR   InterPro; IPR044149; Nitrilases_CHs.
DR   PANTHER; PTHR46044:SF4; CYANIDE HYDRATASE; 1.
DR   PANTHER; PTHR46044; NITRILASE; 1.
DR   Pfam; PF00795; CN_hydrolase; 1.
DR   SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR   PROSITE; PS50263; CN_HYDROLASE; 1.
DR   PROSITE; PS00920; NITRIL_CHT_1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000194280}.
FT   DOMAIN          8..287
FT                   /note="CN hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS50263"
FT   ACT_SITE        48
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10139"
SQ   SEQUENCE   358 AA;  39850 MW;  BA72089A0731E0F3 CRC64;
     MAPTLLKYKA AAVNAEPGWL DLELSVKKTI HWINEAGKNG CKLIAFPELW IPGYPYWMWK
     VNYQESLPLL KKYRESSLPS DSPQMYRIRA AAKENSIFVS LGYSEVDLNS LYTTQVMIDP
     SGNIINHRRK IRATHVERLV FGDGTGDTTS MVVDTEIGRI GHLNCWENMN PFLKSYAVSL
     GEQVHVAAWP LYPHATTLKY PDPYTNISDS NADIVTPAYA IETASYTLAP FQTISAAGVA
     LQTPPGKTPE DNTIYNGNTR IYGPDGQSLI EKPTDDFEGL VYVEIDLNEG HLSKALNDFG
     GHYMRPDLLR LVVDVDRKDA VSKVKGAGSP EVVRTIERVG LSRPFSELEV PASKEQEN
//