ID A0A1Z8L9Z6_9FLAO Unreviewed; 397 AA.
AC A0A1Z8L9Z6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=CBB74_04205 {ECO:0000313|EMBL:OUT45814.1};
OS Owenweeksia sp. TMED14.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Owenweeksiaceae;
OC Owenweeksia.
OX NCBI_TaxID=1986609 {ECO:0000313|EMBL:OUT45814.1, ECO:0000313|Proteomes:UP000196006};
RN [1] {ECO:0000313|EMBL:OUT45814.1, ECO:0000313|Proteomes:UP000196006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED14 {ECO:0000313|EMBL:OUT45814.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455, ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUT45814.1}.
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DR EMBL; NHBT01000019; OUT45814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z8L9Z6; -.
DR Proteomes; UP000196006; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:OUT45814.1}; Hydrolase {ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|PIRNR:PIRNR005700};
KW Thiol protease {ECO:0000256|PIRNR:PIRNR005700}.
FT DOMAIN 47..139
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00112"
FT ACT_SITE 60
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 328
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 349
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 397 AA; 45321 MW; 0CCBB72943D26005 CRC64;
MKNFLKIITI VIFPISLNGQ VDLINKVSNN GETDTKQFEF TTIYDIEATE VKNQGRSGTC
WSYSSTAFLE SELIRMGKPV IDLSEMYTVR KVYEDKARKY IRLHGHLNFA QGGALPDLFY
VIKNYGALPE DVYKGLNYGT EQNDHGELEA SLKGIIDAVK KKNNGTLSSA WENGFKSVLD
AYLGDEPKSF SIDGKSYTPR SFADDYLGIN ADDYVQLTSF SHHPFYSWFP IEVPDNWTWA
TSYNVPLNKM METIDFALEN GFTISWATDV SERGFSIKNG VAVMPAKPWN EMSDEERVNA
YTGPHEEMIV NQEIRQQGFD NYQTQDDHGM QIVGKVKDQK NGIYYIVKNS WGDLKNPYRN
GYIYASEAFI RYKTISIMLH KDGLPNRIKK ATKNAKW
//
