GenomeNet

Database: UniProt
Entry: A0A1Z8LE00_9BACT
LinkDB: A0A1Z8LE00_9BACT
Original site: A0A1Z8LE00_9BACT 
ID   A0A1Z8LE00_9BACT        Unreviewed;       482 AA.
AC   A0A1Z8LE00;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   16-JAN-2019, entry version 10.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   ORFNames=CBB69_06180 {ECO:0000313|EMBL:OUT47233.1};
OS   Phycisphaera sp. TMED9.
OC   Bacteria; Planctomycetes; Phycisphaerae; Phycisphaerales;
OC   Phycisphaeraceae; Phycisphaera.
OX   NCBI_TaxID=1986611 {ECO:0000313|EMBL:OUT47233.1};
RN   [1] {ECO:0000313|EMBL:OUT47233.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TMED9 {ECO:0000313|EMBL:OUT47233.1};
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 Metagenome-assembled Genomes from the Mediterranean Sea: a
RT   resource for marine microbiology.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OUT47233.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; NHBO01000055; OUT47233.1; -; Genomic_DNA.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756129};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      162    296       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      379    448       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   482 AA;  53940 MW;  6604D9B1AA918A51 CRC64;
     MTNLTKDSSP PLEHDTAGNP TERIGREVAR QVGSRRWDMW FDRTTDFVVE DGRLKVEADS
     RYVADWIERH FREAIQIAAR AELGDDIKVQ MGVRSHPGDS TATTVETTPP PAPDRSTARR
     GRRTGNRDRR ETEPRLDHFE IGDSNRLAFD AASRLGEDLD GATSVLFIHG DCGIGKTHLL
     RGICARRKQR DRRAKVRYLT GEQFTNEYIQ AVRSSDLDNF RRTLRRLDLL AIDDVHFLSN
     KNATQSEFLH TIDAIAMNGG AVAVVCDDHP RTINRFSGPL VSRFLSGMVV RVDRPDRELR
     VRLVKRLASD RGIRLGESAM ETLASRCVGS VRELLGGLTR IDALARLDSA SGGPEEIGSI
     AVQRALGDES MSTGGKPIRL SRILEVVCKE VSVDRDELLS SGRHRRVVLA RGLCAYLARE
     LTNACFPEIA SALGRTTHST VHTADRRIRR QLEADELVSG HSEEMVRLRD LVDEIRQALR
     RS
//
DBGET integrated database retrieval system