ID   A0A1Z8V7V4_9PROT        Unreviewed;       512 AA.
AC   A0A1Z8V7V4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Choline-sulfatase {ECO:0000313|EMBL:OUU55265.1};
GN   ORFNames=CBC21_10570 {ECO:0000313|EMBL:OUU55265.1};
OS   Proteobacteria bacterium TMED61.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1986601 {ECO:0000313|EMBL:OUU55265.1, ECO:0000313|Proteomes:UP000196561};
RN   [1] {ECO:0000313|EMBL:OUU55265.1, ECO:0000313|Proteomes:UP000196561}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TMED61 {ECO:0000313|EMBL:OUU55265.1};
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT   for marine microbiology.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUU55265.1}.
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DR   EMBL; NHDO01000074; OUU55265.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z8V7V4; -.
DR   Proteomes; UP000196561; Unassembled WGS sequence.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR017785; Choline-sulfatase.
DR   InterPro; IPR025863; Choline_sulf_C_dom.
DR   InterPro; IPR000917; Sulfatase_N.
DR   NCBIfam; TIGR03417; chol_sulfatase; 1.
DR   PANTHER; PTHR45953; IDURONATE 2-SULFATASE; 1.
DR   PANTHER; PTHR45953:SF1; IDURONATE 2-SULFATASE; 1.
DR   Pfam; PF12411; Choline_sulf_C; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
FT   DOMAIN          6..346
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   DOMAIN          453..501
FT                   /note="Choline sulfatase enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12411"
SQ   SEQUENCE   512 AA;  58430 MW;  9567E6AD9809A5B0 CRC64;
     MTNPMNVLFL MADQLAPHFL PAYGHPVVKT PRLDEIANNG VVFDSHYSNS PLCVPARAGL
     MTGRMPSAID CFDSGCDYPF SVPTLAHYLR AGGYETVQTG KAHFIGPDQL HGLEKRLTTD
     ICPSDNCWYG IWDDPDRILD WFHTLGNVVT AGIAERSSQQ DHDFDAAHTA VRWLYDYARS
     PEQRPFFLKV SFSHPHDPYV TPPAYWDRYR DDEIDMPVTP NIPLPDRDRH GQWLYRHYDR
     GEYDVTEEHI RRARHGYYGS ISLVDDLVGQ VMDALVSARL DQNTIVVFTA DHGDMLGERG
     AWYKMSFYER SCRVPLMISV PGEAGGRRVT QCTSLIDLMP TLLDLTLDQG CADLVEPIEG
     RSLMSLMSGN TDSWADETRA EILFEGVNAP GLMIRRGARK YVHWEGLPCT LFDLESDPEE
     INNLIDDPAH ADEVADFEHQ VQHDWPLTEL TERVLLKQRR NALVHRALMT GQRTPFDFQP
     FDDASKRFYR GHGNWHEAEA RDFLRFDLAK DE
//