ID   A0A1Z8X1A5_9CHLR        Unreviewed;       428 AA.
AC   A0A1Z8X1A5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0000313|EMBL:OUU77518.1};
GN   ORFNames=CBC30_01185 {ECO:0000313|EMBL:OUU77518.1};
OS   Chloroflexi bacterium TMED70.
OC   Bacteria; Chloroflexota.
OX   NCBI_TaxID=1986676 {ECO:0000313|EMBL:OUU77518.1, ECO:0000313|Proteomes:UP000196464};
RN   [1] {ECO:0000313|EMBL:OUU77518.1, ECO:0000313|Proteomes:UP000196464}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TMED70 {ECO:0000313|EMBL:OUU77518.1};
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT   for marine microbiology.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUU77518.1}.
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DR   EMBL; NHDX01000009; OUU77518.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z8X1A5; -.
DR   Proteomes; UP000196464; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR   PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Transferase {ECO:0000313|EMBL:OUU77518.1}.
FT   MOD_RES         208
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   428 AA;  47471 MW;  1C03B56FEB06CAB1 CRC64;
     MTENLKRETL ALHAGYKPDP TTNSRQVPIY PTTSYVFNDT EHAANLFGLA EFGNIYSRLM
     NPTNDVLEQR IAALDGGIYA LSFSSGQAAI NAAILTIAHS GQNIISSTSL YGGTWTLFTQ
     TFKQLGIEVR FFDPNEPEKI NELVDENSRC VYFESLGNPK NDVPDFEKIS KISHDHGLPV
     ICDNTVMTPF LLRPFEHGVD IVIHSTTKFI GGHGAHIGGV IVDSGNFKWA DDPDKWPEFC
     GPSPSYHGAV LEEALRPLGN LVYLVHIRTH WLRDTGAAMS PFAAWITLQG LETLHLRMER
     HCQNAKEIAE FLNKHKQVEW VNYPGLKSHP DHKRAKKYLP DGQGAIIGFG IKGGKEEAVK
     FIDNVKLLSH LANIGDARTL VIHPASTTHS QLSEEEQKET GVNPEYIRLS IGLENVEDIK
     ADIDQALG
//