ID A0A1Z9ANV0_9GAMM Unreviewed; 456 AA.
AC A0A1Z9ANV0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=PABS domain-containing protein {ECO:0000259|PROSITE:PS51006};
GN ORFNames=CBC55_04885 {ECO:0000313|EMBL:OUV22130.1};
OS Gammaproteobacteria bacterium TMED95.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=1986771 {ECO:0000313|EMBL:OUV22130.1, ECO:0000313|Proteomes:UP000195745};
RN [1] {ECO:0000313|EMBL:OUV22130.1, ECO:0000313|Proteomes:UP000195745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED95 {ECO:0000313|EMBL:OUV22130.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUV22130.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NHEW01000016; OUV22130.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z9ANV0; -.
DR Proteomes; UP000195745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; NF037959; MFS_SpdSyn; 1.
DR PANTHER; PTHR43317:SF9; POLYAMINE AMINOPROPYLTRANSFERASE 2; 1.
DR PANTHER; PTHR43317; THERMOSPERMINE SYNTHASE ACAULIS5; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Polyamine biosynthesis {ECO:0000256|ARBA:ARBA00023115, ECO:0000256|PROSITE-
KW ProRule:PRU00354};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 307..438
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 352
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 456 AA; 49801 MW; 4E4DEED66B58061B CRC64;
MFRMNRLFAF FLLLFFEGVA GTTYQVLFIR QFSSSIGNNA EFTGIIICVF LGAMSLGYKV
GGRDNDSPLR TLGLNFLIMS GFGGVMASSS ISGAFLTNPL IESSHLRLFV YSIFSVGLTA
YFVAQSLPLL LQYKQDGESP ASQSGNALFI STIGSMIGAG LPLPLLAPLI GASATLSFLC
IASTAVGCAL LLKYRLTPFG VFAIFFAILG VVAPVTPYIK SHVDGSAFTS TTYNDVYLRD
DNDVLIMEMN NARMSMRFKS GGSASSYVHY INHQLKLLGK TNKNVLVLGA GGFQIHEGDK
DNHYTYVDID SELLDWAGSY FGVNKEEVNL VAKDARAFLV ENPSKWDVIV LDVFSSADSI
PAHLMTLEFF SLVKSRIGPD GLFVANTVTS GGFRDKLSQK LYNTIHASFP FCQVQQTLAG
NETQLNNVVY TCFSHGSDKG LYRDDKRARH SDFTKT
//
