ID   A0A1Z9D9R4_9ACTO        Unreviewed;       335 AA.
AC   A0A1Z9D9R4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Acyl-CoA desaturase {ECO:0000313|EMBL:OUV53940.1};
GN   ORFNames=CBC75_01290 {ECO:0000313|EMBL:OUV53940.1};
OS   Actinomycetales bacterium TMED115.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales.
OX   NCBI_TaxID=1986615 {ECO:0000313|EMBL:OUV53940.1, ECO:0000313|Proteomes:UP000196314};
RN   [1] {ECO:0000313|EMBL:OUV53940.1, ECO:0000313|Proteomes:UP000196314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TMED115 {ECO:0000313|EMBL:OUV53940.1};
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT   for marine microbiology.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUV53940.1}.
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DR   EMBL; NHFQ01000003; OUV53940.1; -; Genomic_DNA.
DR   Proteomes; UP000196314; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd03505; Delta9-FADS-like; 1.
DR   InterPro; IPR015876; Acyl-CoA_DS.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   PANTHER; PTHR11351; ACYL-COA DESATURASE; 1.
DR   PANTHER; PTHR11351:SF3; STEAROYL-COA 9-DESATURASE; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PRINTS; PR00075; FACDDSATRASE.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          54..267
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
FT   REGION          314..335
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   335 AA;  37158 MW;  C3D01775B1E36493 CRC64;
     MALVQDFEKV DDGDAIFLST PMKITIGIFV VGPTLALLGI IPMIYWGLVS WVDIGLLLGF
     WAITGLGITV GXHRFFTHGS FKAPRPVKIA LALMGSYALQ GSINQWVADH RKHHKFSDEI
     GDPHSPWRFG TSRKAIGKGL VFAHMGWLFS EEQATVDQYA PDIRDDKDLQ RINNAFPIIV
     VMTFLLPGII GGLITWSWLG FLTGIFWGGV VRVAFVHHVT WSINSICHVF GKRPFKSRDL
     ASNVNWLAIP SFGESWHNLH HVDPTXARHG VLKGQIDPSA GLIRMLERVN LAHDVRWPKP
     ERLAKKLIDP SMAPRIRGYQ PPATADVASA SSTTA
//