ID A0A1Z9FBE9_9RICK Unreviewed; 296 AA.
AC A0A1Z9FBE9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=S-adenosylmethionine uptake transporter {ECO:0000256|ARBA:ARBA00019341};
GN ORFNames=CBC91_04140 {ECO:0000313|EMBL:OUV79042.1};
OS Rickettsiales bacterium TMED131.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales.
OX NCBI_TaxID=1986867 {ECO:0000313|EMBL:OUV79042.1, ECO:0000313|Proteomes:UP000196340};
RN [1] {ECO:0000313|EMBL:OUV79042.1, ECO:0000313|Proteomes:UP000196340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED131 {ECO:0000313|EMBL:OUV79042.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transports S-adenosylmethionine.
CC {ECO:0000256|ARBA:ARBA00004028}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
CC {ECO:0000256|ARBA:ARBA00009853}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUV79042.1}.
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DR EMBL; NHGG01000059; OUV79042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z9FBE9; -.
DR Proteomes; UP000196340; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF6; RH69884P; 1.
DR Pfam; PF00892; EamA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022970}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..137
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 296 AA; 33130 MW; F5BCEE146AD8BBE1 CRC64;
MSLRIKSALW MLFASLNFAL LNTLVKYLSN DYHLSQIIFF RSFFAVIFIF PWLLNSGLSS
LKTKSIKLQL GRSAVALAAM YLWFFSISKI PLAEATAINF TAPIFGAICA IVFLGEKIKK
RRFIAIMLSI IGALIIIKPG FNNMSIYLLI ALAASLLMGL AAVFIKKLTM IDHPNSVVFY
MPIFLAIFSF IPCIIYWIKP SLVDGLLLVS TGLIATLAHQ GITRAFSISE TTYVLVFDYL
RLPFTAILAF YIFYEIPSVT VFIGSLIIFI SSIYIINREK VAGKKETTPV ITAKRI
//
