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Database: UniProt
Entry: A0A1Z9GDC2_9BACT
LinkDB: A0A1Z9GDC2_9BACT
Original site: A0A1Z9GDC2_9BACT 
ID   A0A1Z9GDC2_9BACT        Unreviewed;       347 AA.
AC   A0A1Z9GDC2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   08-MAY-2019, entry version 6.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=CBD09_01125 {ECO:0000313|EMBL:OUV91982.1};
OS   Puniceicoccaceae bacterium TMED149.
OC   Bacteria; Verrucomicrobia; Opitutae; Puniceicoccales;
OC   Puniceicoccaceae.
OX   NCBI_TaxID=1986788 {ECO:0000313|EMBL:OUV91982.1};
RN   [1] {ECO:0000313|EMBL:OUV91982.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TMED149 {ECO:0000313|EMBL:OUV91982.1};
RA   Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT   "290 Metagenome-assembled Genomes from the Mediterranean Sea: a
RT   resource for marine microbiology.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OUV91982.1}.
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DR   EMBL; NHGY01000007; OUV91982.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       40    338       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   347 AA;  38130 MW;  6F9587271A83F5BC CRC64;
     MKKITDINIT SKTQLPTPVE LCSKXXRSKD VEQFVVETRN AIXNILXGDD DRLLMVVGPC
     SIHDLEAGRE YARRLAQLSK XLSXRFLIVM RVYFEKPRTT VGWKGLIMDP NLDGTSDIPA
     GLEIARSFLT EVLELXLPTA TELLDPITPX YIADLVCWSA IGARTTESQT HRQMASGLSM
     PLGFKNGTDG NLDVAINAIK AASQPQTFLG IDNEGRANAL TTNGNPNCHI VLRGGSKGPN
     YSEEDLKFAS EKLQSANLKP SIMIDCSHAN XNKNPDLQPT VFEALIQQXI ENKAIIGGMI
     ESNLXSGNQK FPQPKEALEY GVSITDGCID WETTEKILRE AHQQLNA
//
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