ID A0A1Z9H771_9PROT Unreviewed; 587 AA.
AC A0A1Z9H771;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Phosphoribosylformylglycinamidine synthase II {ECO:0000313|EMBL:OUW02019.1};
DE Flags: Fragment;
GN ORFNames=CBD14_01610 {ECO:0000313|EMBL:OUW02019.1};
OS Proteobacteria bacterium TMED154.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1986844 {ECO:0000313|EMBL:OUW02019.1, ECO:0000313|Proteomes:UP000196632};
RN [1] {ECO:0000313|EMBL:OUW02019.1, ECO:0000313|Proteomes:UP000196632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED154 {ECO:0000313|EMBL:OUW02019.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUW02019.1}.
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DR EMBL; NHHD01000011; OUW02019.1; -; Genomic_DNA.
DR Proteomes; UP000196632; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR CDD; cd02203; PurL_repeat1; 1.
DR CDD; cd02204; PurL_repeat2; 1.
DR Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 2.
DR HAMAP; MF_00420; PurL_2; 1.
DR InterPro; IPR010074; PRibForGlyAmidine_synth_PurL.
DR InterPro; IPR041609; PurL_linker.
DR InterPro; IPR010918; PurM-like_C_dom.
DR InterPro; IPR036676; PurM-like_C_sf.
DR InterPro; IPR016188; PurM-like_N.
DR InterPro; IPR036921; PurM-like_N_sf.
DR NCBIfam; TIGR01736; FGAM_synth_II; 1.
DR PANTHER; PTHR43555; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE SUBUNIT PURL; 1.
DR PANTHER; PTHR43555:SF1; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE SUBUNIT PURL; 1.
DR Pfam; PF00586; AIRS; 2.
DR Pfam; PF02769; AIRS_C; 1.
DR Pfam; PF18072; FGAR-AT_linker; 1.
DR SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR SUPFAM; SSF55326; PurM N-terminal domain-like; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755}.
FT DOMAIN 10..56
FT /note="Phosphoribosylformylglycinamidine synthase linker"
FT /evidence="ECO:0000259|Pfam:PF18072"
FT DOMAIN 77..201
FT /note="PurM-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00586"
FT DOMAIN 214..366
FT /note="PurM-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02769"
FT DOMAIN 451..570
FT /note="PurM-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00586"
FT NON_TER 587
FT /evidence="ECO:0000313|EMBL:OUW02019.1"
SQ SEQUENCE 587 AA; 63128 MW; F7C39267F0605BF1 CRC64;
MPPEPTPEEI STQQSYLSLG LSDSEYQLVC ELLGRKPNLT ETGIYGVMWS EHCSYKTSKM
QLSRFPTEGP NVLQGPGEGA GVVDLGDGWA VVFKVESHNH PSAIEPYQGA ATGVGGILRD
IYSMGARPVA FLNSLRFGPL SDKKDPGSPN SKRNQYLFGG VVAGIAGYGN CIGVPTVAGE
VGFDACYSGN PLVNAMCVGV IRHEDLQHGR AEGIGNPVIY VGAATGRDGI HGATFASEEL
NEESEAKRPS VQVGDPFMGK LVLEACLELF RSGAVISVQD MGAAGLTCSS TEMAEKGGNG
MELDLDLVPQ RALEMSPYEI MLSESQERML LVAKAGREEE VFEICRKWEV PACTIGRVIP
ETVLRLKHRG ALAAELPLDR LLGSCPLYQR DAVPSEKQLS RQKKNAVXWD VPDDIGALFK
EMIVQPELAS KRWVYRQXDS MVRTCTSVGP GSDAAVIRIE GTNKALAMSI DGNSRYVELD
PQTGGRIAVA EAARNVTCSG GRPLALTNGL NFGNPEKPEI FWQLREAVTG ICEACQSLEL
PVTGGNVSLY NETDGEAVYP TPLIGVVGLV EHPEHETTQH WKQAGDV
//
