ID A0A1Z9LE00_9CYAN Unreviewed; 555 AA.
AC A0A1Z9LE00;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=CBD48_06465 {ECO:0000313|EMBL:OUW53462.1};
OS Cyanobacteria bacterium TMED188.
OC Bacteria; Cyanobacteriota.
OX NCBI_TaxID=1986678 {ECO:0000313|EMBL:OUW53462.1, ECO:0000313|Proteomes:UP000195725};
RN [1] {ECO:0000313|EMBL:OUW53462.1, ECO:0000313|Proteomes:UP000195725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED188 {ECO:0000313|EMBL:OUW53462.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUW53462.1}.
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DR EMBL; NHIL01000049; OUW53462.1; -; Genomic_DNA.
DR Proteomes; UP000195725; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OUW53462.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 329..453
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
FT REGION 534..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 62829 MW; D0B213679B8C2481 CRC64;
MQAFQALFQD LDEVTGTRAK VHALCAHFQN VLPLEAAWTL HLLLGKRRRR LITGRRLRDI
LRDQGGMPDW LIEDCHAQVG DSAETISLLW PAVKDQIAFC DAGLPTIEPS HPLSWWMETL
LPAISTRSDD DQAXAVIQLW QSIPSEQHFI VNKLLTGGFR VGVSTGLISR AIAEAFALEE
SLVVQRLMGG FTPSAENXER LTLPASTEEH RSSGTPYPFF LASPLEPERL SDTDPDQWQL
EWKWDGIRGQ LIHRGSGVYL WSRGEELVND SFPELTSVAE ALPAGTVLDG EVICWSQNDP
SPLGFDQLQR RLGRKTVGAT LKRECPMRFI AYDLLEHNGV DIRHHPLKER QQRLAVLLKH
VDHPEAWRLN QSQSWALTAW AALDQERDRA RTHKAEGXML KXGDSPYLSG RKRGYWWKHK
LEPMTLDAVL LYAQAGSGRR ANLFTDYTFG LWSDDTPSQL VTFAKAYSGL NDAEILELDR
WIRRNTVERF GPVRSVKPEL VFEIGFEGIH PSKRHKSGIA VRFPRILRRR PDKPAEEADR
LDTARNLIRD GSSSG
//
