ID A0A1Z9LHA8_9CYAN Unreviewed; 390 AA.
AC A0A1Z9LHA8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Efflux transporter periplasmic adaptor subunit {ECO:0000313|EMBL:OUW54753.1};
GN ORFNames=CBD48_04445 {ECO:0000313|EMBL:OUW54753.1};
OS Cyanobacteria bacterium TMED188.
OC Bacteria; Cyanobacteriota.
OX NCBI_TaxID=1986678 {ECO:0000313|EMBL:OUW54753.1, ECO:0000313|Proteomes:UP000195725};
RN [1] {ECO:0000313|EMBL:OUW54753.1, ECO:0000313|Proteomes:UP000195725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED188 {ECO:0000313|EMBL:OUW54753.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUW54753.1}.
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DR EMBL; NHIL01000036; OUW54753.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z9LHA8; -.
DR Proteomes; UP000195725; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 88..313
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 314..343
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 173..200
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 42124 MW; ABD1708EB638BF80 CRC64;
MLQTLRRATP PATAPSEATN PAAAKPRQRS RPLTIGLVLL ALCGGGLLLR FSPLGNRPRD
IAPFTTTAER GMLSGVITAS GELQAIQRVN VSPLKQGLLE QLLVDEGDVV QNDQLLAVMD
RGDLDDRLQE REALLRQAEA TYNIRKDDFD RRSALYRIGV ISADDFSDVR FEMLAAQAAV
IAARERVEQL EEEQSELKIR APFAGTITAR YAEPGAFVTP TTTASATAGA TSSSIVELSQ
GLEVSARVPE SDIGRIVTGQ AAEIRVDAFP DERFAARVSE IAPRAEKEDN VTSFEVKLDL
VNPPKKLRIG MTADIDFQTG RSATKTLVPT VAIVTENGKP GVLVVDDKQQ PSFQQVELGN
SSGDQTAILK GLDAGTRVFI DLPPWADPRD
//
