ID A0A1Z9QFY7_9BACT Unreviewed; 783 AA.
AC A0A1Z9QFY7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBD91_01080 {ECO:0000313|EMBL:OUX03039.1};
OS Phycisphaeraceae bacterium TMED231.
OC Bacteria; Planctomycetota; Phycisphaerae; Phycisphaerales;
OC Phycisphaeraceae.
OX NCBI_TaxID=1986831 {ECO:0000313|EMBL:OUX03039.1, ECO:0000313|Proteomes:UP000196960};
RN [1] {ECO:0000313|EMBL:OUX03039.1, ECO:0000313|Proteomes:UP000196960}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED231 {ECO:0000313|EMBL:OUX03039.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUX03039.1}.
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DR EMBL; NHKC01000010; OUX03039.1; -; Genomic_DNA.
DR Proteomes; UP000196960; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..330
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 374..761
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 86229 MW; 02D2AA67450612CF CRC64;
MIRMHRADEP TEDPAPTSTS DSIRSRGDRI AKLLLWGTTA LLATAFLRTV QLQVWPDETV
LSLMGRRHAT VAEIRPRGDI YDRKGRLIAT TVLGHDLGVD PKFLMDAADK VTNDAGEPIA
NPIAWLAELV SMHTGIDREM LEDRLGPEII VDVAALMRTA AEHGEEDPLT PLAAAVARTT
GMDRADVESI LFNDLDATRV VLAGPRDLRA TNLRDFRATL PDAVILEGLD DRYVRLARAE
DLRDVDLAML RSELPPGVVL TARPERRLNT RTLASSLVGS VGAYEPPNAR LGTEGRQRGR
SGVEHARDGR LKQTRGRMTY QKDARGRATE VRDGDYIPGD DGHDVDLSID LVIQRIAETR
LAEAVAAHHA VGGWILVVDP RTGDVLAAHD ILDNAEARRR GPTIWPPNAL DPARDELGAA
HARNRVWTDV YEPGSTFKTM FWAWAVQRGL AKPGETIADR SGRTTPGGGF TTSGLSFSFP
GERGNRRVRD AYGKSKSDWS TCLEKSLNTG MAMVALRMAE DDRRRGLDIG AGMHEMFRGF
GFSYRTGIDM GSAEQTGRIT PRFITDPRSG ERKRTWFPLW SQITVSFGQE IAVTPLQMIR
AYCPIARNDG RLPALRLIRP TTPGIQAVPT SQVLDRETVM KTRTVLRRVV ENVNRKFERP
ERGYELWGKS GTAQRVRYVA KTGAATGERT WTPDGYWDRD VHGTGHYNSS FIGAGPFEDP
KLIVACCLED PDVASGLNIE INNGRGYYGS SSAGPVVLDV LEASLEYLGX RPDVDPTIVA
AED
//
