ID A0A1Z9RJS8_9RICK Unreviewed; 363 AA.
AC A0A1Z9RJS8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=alanine racemase {ECO:0000256|ARBA:ARBA00013089};
DE EC=5.1.1.1 {ECO:0000256|ARBA:ARBA00013089};
GN ORFNames=CBE11_01190 {ECO:0000313|EMBL:OUX16763.1};
OS Rickettsiales bacterium TMED251.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales.
OX NCBI_TaxID=1986870 {ECO:0000313|EMBL:OUX16763.1, ECO:0000313|Proteomes:UP000195709};
RN [1] {ECO:0000313|EMBL:OUX16763.1, ECO:0000313|Proteomes:UP000195709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED251 {ECO:0000313|EMBL:OUX16763.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600821-50};
CC -!- SIMILARITY: Belongs to the alanine racemase family.
CC {ECO:0000256|ARBA:ARBA00007880}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUX16763.1}.
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DR EMBL; NHKW01000008; OUX16763.1; -; Genomic_DNA.
DR Proteomes; UP000195709; Unassembled WGS sequence.
DR GO; GO:0008784; F:alanine racemase activity; IEA:InterPro.
DR GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR CDD; cd00430; PLPDE_III_AR; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR NCBIfam; TIGR00492; alr; 1.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR600821-50}.
FT DOMAIN 239..361
FT /note="Alanine racemase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01005"
FT BINDING 138
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT BINDING 306
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT MOD_RES 39
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ SEQUENCE 363 AA; 41283 MW; A9E52AF78FD6242A CRC64;
MNIIEESNAR LFIKLKSFKK NWHYLNSLSK NKNIGLSVKA NCYGLGLKIM CKTLVNEGCQ
NFFVANSTEA LQLRKILKNV NIYVLNGIKD IMIAKKLIQK NIFIVINNHQ DLKIVKKCLS
TKKEKISCAV HFDTGMNRLG FSEKDIFLIS RSIEKYLDPK LVISHLSNSE NKTSKFNKFQ
LSRFKKIKDI LDKKFKLKYS LANSNGIFLG KSFHFDLIRT GGLAFGLHLK NKKNNIKNII
SLKAKIIQIR LLEQGSPIGY GSKYITRKKS LIATLAIGYA DGIPRNYKGY FFLKGKKVKI
CGNISMDLTC XDVTGIXXIK VNDWVEIFGX NIPVEXFAFL SXTISYDILS SLGNRIERVY
LNS
//
