ID A0A1Z9WQP1_9GAMM Unreviewed; 527 AA.
AC A0A1Z9WQP1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=CBC19_01860 {ECO:0000313|EMBL:OUX80044.1};
OS Oceanospirillales bacterium TMED59.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales.
OX NCBI_TaxID=1986765 {ECO:0000313|EMBL:OUX80044.1, ECO:0000313|Proteomes:UP000195499};
RN [1] {ECO:0000313|EMBL:OUX80044.1, ECO:0000313|Proteomes:UP000195499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TMED59 {ECO:0000313|EMBL:OUX80044.1};
RA Tully B.J., Sachdeva R., Graham E.D., Heidelberg J.F.;
RT "290 Metagenome-assembled Genomes from the Mediterranean Sea: a resource
RT for marine microbiology.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUX80044.1}.
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DR EMBL; NHDM01000021; OUX80044.1; -; Genomic_DNA.
DR Proteomes; UP000195499; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OUX80044.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 314..428
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 527 AA; 59594 MW; E770E684485E70B4 CRC64;
MNFVQLFQIL DTSQSTNAKR NGLVEFIQTA DPLESALAVE ALTGRRDRKQ LKPSLLKQAA
YQAFADESWL FDECYAAVGD LSETLAILFT KQDAVSQTAQ PILDQWRQRQ HALSQQKPEV
LISELPSLLN TLSRDEAFLF LKLSSGGFRV GVSKGLVHEA IARAINMDRA VIEERLMGDF
PPDPDWLDRL KAPVTQDELD AKPLPFLLAN PISESEISAL NPTDVLVEYK WDGIRAQLIK
THETIRLWSR GDQDITEQFP DIVEVATTLP SQMILDGEIL AGTTEHLQTF NDLQTRLNRK
RITQTLLKTH PAFFKAYDLL RLDGEDLRGH PLIARKAALS KITVSQSLTM HPMCSKSIHA
MRQEAREKGA EGVMIKCKQS CYVAGRKAGH WWKWKLDPMT ADXVLIYAQA GHGRRASLHS
DYTLACWNQD NELVPVAKAY SGLTDAELKD MDQWIRKHTL QKFGPVRQVE AFHVFEIGFE
GIARSTRHKS GIALRFPRIL RWRQDIGPKD ADHLTHFEAL MSXXHAV
//
