ID   A0A200JG15_9ENTE        Unreviewed;       897 AA.
AC   A0A200JG15;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A5889_001216 {ECO:0000313|EMBL:OUZ35740.1};
OS   Enterococcus sp. 9D6_DIV0238.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1834192 {ECO:0000313|EMBL:OUZ35740.1, ECO:0000313|Proteomes:UP000196151};
RN   [1] {ECO:0000313|EMBL:OUZ35740.1, ECO:0000313|Proteomes:UP000196151}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9D6_DIV0238 {ECO:0000313|EMBL:OUZ35740.1,
RC   ECO:0000313|Proteomes:UP000196151};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genomic Center for Infectious Diseases;
RA   Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA   Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterococcus sp. 9D6_DIV0238.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUZ35740.1}.
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DR   EMBL; NIBQ01000001; OUZ35740.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A200JG15; -.
DR   OrthoDB; 2323731at2; -.
DR   Proteomes; UP000196151; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR   Gene3D; 3.10.20.320; Putative peptidoglycan bound protein (lpxtg motif); 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR005046; DUF285.
DR   InterPro; IPR022038; Ig-like_bact.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011889; Liste_lipo_26.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   NCBIfam; TIGR02167; Liste_lipo_26; 3.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   Pfam; PF07523; Big_3; 4.
DR   Pfam; PF03382; DUF285; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196151};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        872..889
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          545..610
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|Pfam:PF07523"
FT   DOMAIN          619..685
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|Pfam:PF07523"
FT   DOMAIN          696..760
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|Pfam:PF07523"
FT   DOMAIN          769..835
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|Pfam:PF07523"
FT   DOMAIN          855..894
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|Pfam:PF00746"
FT   REGION          44..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          837..868
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..64
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        837..866
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   897 AA;  99467 MW;  2FF22B224455E481 CRC64;
     MKKRMLSMFS LVVLVASYTS GIVSVYAESI ETIKEPMVYV SEEEQVQNEE VSTETSSQSA
     EESIDQVESS DDAYDLEGNE LNSSISEERN VETQNTTELN ELSDDLYSGT FGTSDWRIDS
     NGILHIGAGN FESTNGESPW ITYSDQINRI VFEGKVVAHS NSKYLFSKFP NLESIENLEL
     LDTSQATLMN NMFSMCPKLR SLDVSTFNTS SVTDMGGMFA YNPGLVSLNV SGLDLSRTWF
     LNLMFAECSS LKELDVSSFR TPVNGMGSMF AMFRDCSSLE YLDLSGFDMM KINSNINREF
     LAGTTSLTKL KLGSKVRFTN VEALPDVPTN TQYTGKWQNV GDGTPESPNG SYVFTSKELT
     AFNNYQGSEM AGTYVWQPTQ VEQTGDIIIS YVDTFGNNIS DPVTGFEIQP VTFSGKIGDA
     ADDDLYYVDA SGWVLLTELP TGIVYGKNPQ NYKMVYDNAG TIYVNYEDTL GNKLKAEERN
     TEYISKFDWS SGNLPESVAY EIETIEMDGY NFIGTEGDPK TGNIEAYEIK RITFKYEKID
     YSSLNVHDST IQVGESWNAA DNFDSATDKD GNSVDFEDVT VKGFVDTTKE GEYEISYSYE
     ETTSIAKITV KAKEAAPIIN VQDSSIQVGD TWKAADNFIS AFDKNGKLLD FSEIKVTGEV
     DTTKEGEYEV SYSYEETTSV AKIAVKAKEA APIINIQDSS IQVGDNWKAS DNFISAFDKN
     DDPLDFSEIK VTGEVDTAKP GKYEVSYSYE ETTSVAKITV KAKEVAPIIN VHDSSIQLGD
     NWKASDNFTS AFDRLGNAVE FKTISIEGTV DTKKVGTYEV KYSYDGISAV AKITVKDNKK
     TSDKPHSNHK NSKTKENKKQ QLPKTGEKTR RIGTFVGSGL ILVIVLFLVK KRKNTSY
//