ID A0A200PPK5_9MAGN Unreviewed; 755 AA.
AC A0A200PPK5;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 08-NOV-2023, entry version 20.
DE SubName: Full=Peptidase S8/S53 domain {ECO:0000313|EMBL:OVA00151.1};
GN ORFNames=BVC80_1671g14 {ECO:0000313|EMBL:OVA00151.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA00151.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA00151.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA00151.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA00151.1}.
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DR EMBL; MVGT01004352; OVA00151.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A200PPK5; -.
DR STRING; 56857.A0A200PPK5; -.
DR InParanoid; A0A200PPK5; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF541; SUBTILISIN-LIKE PROTEASE SBT4.14; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000195402};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..755
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012984561"
FT DOMAIN 39..117
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 139..591
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 649..749
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 147
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 212
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 540
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 755 AA; 80721 MW; E09AE0E384B6F97F CRC64;
MSIRDESTQV LFRRLLLLQV ILSGLASVNG SDDQQKNFYI VYMGDSPSSL KDSIVESHVN
LLSSVVGSVG AAKDSIVHSY INNFNAFAAK LSPNEAKMLE RSSSVISVFP NQYRKLHTTK
SWDFMGFNQN VKRNLKLESN IVVGLLDTGI TPGSESFSDK GLGPPPAKWK GTCGPFANFS
GCNNKLVGAR FFKLDGNPDP TDIMSPVDVE GHGSHTSSTV VGNVVNGADL FGLAKGTARG
AVPSARVAMY KVCWASSGCS DMDLLAGFDA AIEDGVDVIS VSIGGSSESY LRDPIAIGAF
HAMKKGIITV ASAGNEGPGL SSVVNHAPWI LTVAASGIDR QFRSKIMLGN GKLLSGIGIN
TFTPKQRLYP LISGADAGFN SSVDPSTSSM YCMGDSLDPK KVKGKVVLCE LQQWGADSVV
KKAGGTGTLL ESSINPDTAQ IFMAPGTMIN YSIAKDINDY ISSTRSPSAV IYRTQEVKVS
APFVASFSSR GPSMGSRHVL KPDITAPGID ILAAYTPLKS LTGLDGDKQY SKFTIMSGTS
MSCPHVAGVA AYVKSFHPAW SPAAIKSAII TTAKPMSPKV NVGAEFSYGA GLLNPIQAVH
PGLIYDMDQL PYIQFLCFEG YKDDPIRVIV GSRTVNCSEL PPAQGSDALN YPTMQLSMKT
SDKKPGIAVF RRRVTNVGPA KSIYNATINA PKNVEITVNP TNLVFTRRFQ KRSFKVVVKA
KTVASEQEIQ SGSLVWRSDI HTVRSPIVVF TSDYF
//
