ID A0A200QDA6_9MAGN Unreviewed; 370 AA.
AC A0A200QDA6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:OVA08425.1};
GN ORFNames=BVC80_209g159 {ECO:0000313|EMBL:OVA08425.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA08425.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA08425.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA08425.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA08425.1}.
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DR EMBL; MVGT01002328; OVA08425.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A200QDA6; -.
DR STRING; 56857.A0A200QDA6; -.
DR InParanoid; A0A200QDA6; -.
DR OrthoDB; 103196at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580:SF10; GLYOXYLATE_SUCCINIC SEMIALDEHYDE REDUCTASE 2, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000195402}.
FT DOMAIN 79..237
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 240..359
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
SQ SEQUENCE 370 AA; 39087 MW; 5406AAC283AC4DE9 CRC64;
MADMLSTMLL ANSMIKTSST TMAIMCSSSS TFVPQIHNNF KRRPISSFPT KPLFSVSPKA
FSSQTSNPTS KADEPPTSVG FLGLGIMGSP MAQNLLRAGC DVTVWNRTKS KCDPLISLGA
KYKTSPEEVA SSCDVTFAML ADPESALEVA CGKHGAAYGM TQGKGYVDVS TVDDATSKLI
SRQIKATGAL FLEAPVSGSK KPAEDGQLIF LTAGDKSLYD AVAPLLDIMG KSRFYLGDVG
NGAAMKLVVN MIMGSMMASF SEGLLLSEKV GLDPSVLVEV VSQGAISAPM FSMKGPSMVQ
AIYPTAFPLK HQQKDLRLAL GLAESVSQPT PIAAAANELY KVAKLHGLSD QDFSAVMEAL
KTRLQSPAED
//
