ID A0A200QX35_9MAGN Unreviewed; 977 AA.
AC A0A200QX35;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Amino acid permease/ SLC12A domain {ECO:0000313|EMBL:OVA14992.1};
GN ORFNames=BVC80_67g17 {ECO:0000313|EMBL:OVA14992.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA14992.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA14992.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA14992.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA14992.1}.
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DR EMBL; MVGT01000927; OVA14992.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A200QX35; -.
DR STRING; 56857.A0A200QX35; -.
DR InParanoid; A0A200QX35; -.
DR OrthoDB; 5490251at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR NCBIfam; TIGR00930; 2a30; 1.
DR PANTHER; PTHR11827:SF100; CATION-CHLORIDE COTRANSPORTER 1; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000195402};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..604
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 645..766
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 777..976
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 107279 MW; D249509F0E170FA6 CRC64;
MENGEIESQD DDLPSQTGRQ YRPVVAHDRA VLEMSSMESG SSSRDTPLKN IKVSSTLESD
VGEASTPTQS GHNRLQRDSK LELFGFDSLV NILGLKSMTG EQIAAPSSPR DGEDVSITLG
RPKPNDVKLG TLMGVFVPCL QNILGIIYYI RFTWIVGMAG IGESLLLVSF CGLCTFLTGI
SLSAIATNGA MKGGGPYYLI GRALGPEVGV SIGLCFFLGN AVAGSMYVLG AVETFLDAVP
AAGIFRGSVT SVNATSGVAE SIQTPSIHDL QVYGIVVTIL LCFIVFGGVK MINRVAPAFL
IPVLFSVFCI FAGIFIAKKD QPSPGITGLS AKTFKDNWSS DYQRTTSSGV PDPDGEIYWN
FNAMVGLFFP AVTGIMAGSN RSASLKDTQR SIPIGTLAAT LTTSALYLIS VLFFGALATR
EKLLKDRLLT ATVAWPIPAI IYVGIILSTL GAALQSLVGA PRLLAAIAND DILPVLNYFK
VADGNEPYLA TLFTAFICIS CVVIGNLDLI TPTITMFFLL CYAGVNLSCF LLDLLDAPSW
RPRWKFHHWS LSLLGALLCI VIMFLISWSF TVVALALASL IYYYVSLKGK AGDWGDGFKS
AYFQLALRSL RSLGASQVHP KNWYPIPLIF CRPWGKLPEN VPCHPKLADF ANCMKKKGRG
MSIFVSILDG DYHECAEDAK TACRQLSTYI DYKRCEGVAE IVVAPNMSDG FRGIVQTMGL
GNLKPNIIVM RYPEIWRREN LIEIPATFVG IINDCIVANK AVVIVKGLDE WPNEYQRQYG
TIDLYWIVRD GGLMLLLSQL LLTKDSFESC KIQVFCIAEE DTEAEELKAD VRKFLYDLRM
QAEVIVITMK SWEVHVEGGA QQDDSIEAFT GAQRRIAAYL GEMKEKARKD GTPLMADGKR
VVVNEQQIEK FLYTTLKLNS TILRYSRMAA VVLVSLPPPP LNHPPYFYME YMDLLVENVP
RLLMVRGYRR DVVTLFT
//
