ID A0A200R0E5_9MAGN Unreviewed; 616 AA.
AC A0A200R0E5;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=XPG/Rad2 endonuclease {ECO:0000313|EMBL:OVA16161.1};
GN ORFNames=BVC80_8929g23 {ECO:0000313|EMBL:OVA16161.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA16161.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA16161.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA16161.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA16161.1}.
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DR EMBL; MVGT01000628; OVA16161.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A200R0E5; -.
DR STRING; 56857.A0A200R0E5; -.
DR InParanoid; A0A200R0E5; -.
DR OrthoDB; 26655at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0004520; F:DNA endonuclease activity; IEA:UniProt.
DR CDD; cd09869; PIN_GEN1; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11081:SF59; FLAP ENDONUCLEASE GEN-LIKE 1; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:OVA16161.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000195402}.
FT DOMAIN 1..96
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 128..198
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 535..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 69776 MW; 7A4A75CE672CB6B8 CRC64;
MGVGGNFWDL LKPYAQNEGF DFLRNKKVAV DLSFWIVQHE TALKNKARNP HLRLTFFRTI
NLFSKLGAFP VFVIDGVPSP LKARARIERF FRFSGIDLSG LPMAEDGVSV ERNGAFTKCV
RECVELLEIL GMPILKASSE AEALCAQLNS EGHVDACITA DSDAFLFGAK CVIKCLRPTS
KEPFECYHMS DIEAGLGLKR THLIAISLLV GNDHDLGGVS GVGIDTALQF VQMFPEDEIL
SRLQKVGNGD IPSSQISTES FVDRDIRGPD GSSPKTKSPH CSYCGHPGTK RAHLKLACEY
CTVNCNENCM QKPVGFKCEC SSCVMDRKSK EQKKQKNWLI NVCSKIAMEQ NFPNDEIVDM
YLRHNHGNIK HESISLLWEK PKIDTLIDFL GYHQQWDPSY IRQRLLPMLS TIFLREMASN
PTEGLLLHEQ YEFHSIQRVK IRYGHPCYLV NWKKIAPVGN ANYTIRTEEC DIQQEGILEV
SESIDLLDDP DVPEIRVDDG CWFLLTDENM ELVQAAFPEE VNRFLQEKEK KESKLRKRKS
VVKSEGDQKK SETPKSSGVQ LSITEFYRSK KVSVSAKQEE EPVNNYENQA KGSSTERRNM
SSPNLSKSVR RRLLFD
//
