ID A0A200R1P4_9MAGN Unreviewed; 2511 AA.
AC A0A200R1P4;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ABC transporter {ECO:0000313|EMBL:OVA16637.1};
GN ORFNames=BVC80_1543g71 {ECO:0000313|EMBL:OVA16637.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA16637.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA16637.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA16637.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA16637.1}.
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DR EMBL; MVGT01000481; OVA16637.1; -; Genomic_DNA.
DR STRING; 56857.A0A200R1P4; -.
DR InParanoid; A0A200R1P4; -.
DR OrthoDB; 5487044at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 2.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 2.
DR CDD; cd03249; ABC_MTABC3_MDL1_MDL2; 4.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR43394:SF11; ALPHA-FACTOR-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR43394; ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL; 1.
DR Pfam; PF00664; ABC_membrane; 4.
DR Pfam; PF00005; ABC_tran; 4.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS50929; ABC_TM1F; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 4.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000195402};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 692..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 812..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 837..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 912..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 951..969
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1287..1312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1332..1354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1406..1426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1432..1453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1510..1533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1548..1574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1943..1967
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1987..2012
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2090..2112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2169..2192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2207..2225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..359
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 394..630
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 694..980
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1015..1252
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1291..1574
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1610..1846
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1947..2233
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 2268..2505
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1241..1266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2511 AA; 272972 MW; 97694A0B91F8EBF3 CRC64;
MDEKNGLNGT IDKRRGTTSM SHSPLTETDK FAGMTADQQD SETSKGEEEI INIVPFFKLF
SFADSKDLVL MVVGTIAALA NGGTMPFMSV LFGNLVNSFG RTAGTDNVLK EVSKVALDFT
YLAVFSGVAS FFQVACWMVT GERQAARIRN LYLKTILRQD IAFFDKETNT GEVVGRMSGD
TVLIQDAMGE KVGRFIQLIA TFLGGFIIAL IKGWLLTLVM VSSIPPLAIS SAVMTIFIAK
MASRGQVAYS QAGIIVEQTV GSIRTVASFT GEKQAITKYN KSLASAYKSG VQEGLATGLG
YGSVIFIAFC SYALAVWFGA RMIIDKGYTG GDVINIIVAV LTGSMSLGQA SPCLGAFAAG
QAAAFKMFET INRKSEIDAY DTNGKILDDI RGDIELRDIY FSYPTRPNEQ IFNGFSLCIP
RGTTSALVGQ SGSGKSTVIS LIERFYDPQA GEVLIDGINL KEFQLRWVRE RIGLVSQEPM
LFTSSIKDNI AYGKDGATFE EIRVAAELAN AAKFIDKLPQ GLDTLVGEHG TQLSGGQKQR
IAIARAILKD PRILLLDEAT SALDTKSELI VQEALDRIMV NRTTVIVAHR LSTVKNADMI
AVVHQGKIVE KGSHLELLKD PEGAYCQLIR LQEVSRESEN DIEEPEIMLD SWRHSSKHMS
FRRSISHGSS GQQAQKVPLW RLVYLNKPEL PVLLLGIISA AINGVVFPAF SVMLAGIIKT
FYEPPSELRK DSRFWAMMFL VLGIVSLVAS PARAYFFAVA GCKLITRIRL MCFEKVIHMD
IGWFDEPEHS SGAIGARLSA DAATVRSLVG DALALLVQNT ATTIAGLAIA FEANWQLALI
VLLFLPMLGL NGWLQVKVLS GFSADAKMMY EEASQVANDA VGSIRTVASF CAEEKVMKLY
EKKCEGPRKT GIRLGFISGI GYGVSFFLLF CVYAASFYFG GRLVQEGKTT FPMVFRVFFA
VTMTAIGVSQ SSSMAPDSSK AKNSTASIFA ILDKKSKIDS SDDSGMTLDD VKGEIEFQHV
SFKYPIRPDV LIFRDLCLSI HSGKTVALVG ESGSGKSTVI SLLQRFYDPD AGQITLDGIE
IQKFQVRWLR QQMGLVSQEP ILFNDTIRAN IAYGKEGNAT ETETFAAAKQ ANAHKFISGL
QQGYDTIVGE QGIQLSGGQK QRIAIARAIV KEPKILLLDE ATSALDAESE RVVQDALYQV
MVNRTTIVVA HRLTTIMNAD LIAVVKNGVI CEKGNHDTLI DIKDGKDNNS SGKTADQQES
EHSKEEEEIV KTVPFFKLFS FADSKDVMMM VVGTIAALGN GGTMPLMTVL FGQMVDAFGQ
TAGTKDVLKE VSKVYICCKT LIIHSFSVTC WMVTGERQAA RIRSFYLKTI LRQDIAFFDK
EANTGEVVGR MSGDTVLIQD AMGEKVVGKF IQLTATFLGG FIIAFVKGWL LTLVMLSSIP
LLAISGAAMF IFIGKMASRG QTAYSQAGIV VEQTVGSIRT VASFTGENQA ITKYNKSLAS
AYKTGVQEGL VSGLGLGLVL FIMFCSYALA IWFGARMIIE KGYTGGDIIN IIVAVLTGSM
SLGQASPCLG AFAAGQAAAF KMFETINRKP EIDAYDTSNG KILDDIRGDI ELRDVHFSYP
ARPDEQIFNG FSLCIPSGTT SALVGQSGSG KSTVISLIER FYDPQAGEVL IDGINLKEFQ
LRWVRGKIGI VSQEPVLFTS SIKDNIAYGK DGATLEEIRV AAELANAAKF IDKLPQGLDT
LVGEHGTQLS GGQKQRIAIA RAILKNPRIL LLDEATSALD AESERIVQEA LDRVMVNRTT
IIVAHRLSTV RNSDMIAVIN QGKIVEKGSH IELLKDPDGA YCQLIRLQEV NKESGKDKEK
QEIIVESGRH SSKHMFLPRS ISRGSSGRGS SSRHSFSVSF GLPTALNIQE TSSEDRATVL
LPPKEKAKEV SIRRLLYFNK PELPILLLGV ISAAVNGVVF PAFSVMLSGI IKTFYEPPSE
LRKDARFWAL MFILLGVVSL VASPARTYFF AIAGCRLIKR IRAMCFEKVV HMDIGWFDEP
EHSSGAIGAR LSADAASVRS LVGDALGLLV QNTATTIAGL AIAFEANWQL ALIVLFLLPL
IGINGWIQIK FVTGFSADAK MMYEEASQVA NDAVGSIRTV ASFCAEEKVM KLYEKKCEGP
RRTGIRQGLI SGVGYGVSFF LLFCVYAASF YIGGRLVEEG KTTFPKVFRV FFALILTAIG
VSQSSSMAPD SSKAKTSTAS IFAILDQKSK IDSSNDSGLT LDDVKGEIEF QHVSFKYPIR
PDVQIFRDLC LAIHSGKTVA LVGESGSGKS TVISLLQRFY DPDSGHITLD GIEIQKFQVK
WLRQQMGLVS QEPVLFNDTI RANIAYGKEG NATETETLAA AEQANAHNFI SGLQQGYDTI
VGERGVQLSG GQKQRVAIAR AIVKGPKILL LDEATSALDA ESERVVQNAL DRVMLNRTTV
VVAHRLTTIK NADVIAVVKN GVIAEKGNHD TLIDIKDGVY ASLVALHMNS S
//
