ID A0A200R1W7_9MAGN Unreviewed; 2798 AA.
AC A0A200R1W7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=ABC transporter-like {ECO:0000313|EMBL:OVA16670.1};
GN ORFNames=BVC80_1543g105 {ECO:0000313|EMBL:OVA16670.1};
OS Macleaya cordata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Macleaya.
OX NCBI_TaxID=56857 {ECO:0000313|EMBL:OVA16670.1, ECO:0000313|Proteomes:UP000195402};
RN [1] {ECO:0000313|EMBL:OVA16670.1, ECO:0000313|Proteomes:UP000195402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BLH2017 {ECO:0000313|Proteomes:UP000195402};
RC TISSUE=Root {ECO:0000313|EMBL:OVA16670.1};
RX PubMed=28552780; DOI=.1016/j.molp.2017.05.007;
RA Liu X., Liu Y., Huang P., Ma Y., Qing Z., Tang Q., Cao H., Cheng P.,
RA Zheng Y., Yuan Z., Zhou Y., Liu J., Tang Z., Zhuo Y., Zhang Y., Yu L.,
RA Huang J., Yang P., Peng Q., Zhang J., Jiang W., Zhang Z., Lin K., Ro D.K.,
RA Chen X., Xiong X., Shang Y., Huang S., Zeng J.;
RT "The Genome of Medicinal Plant Macleaya cordata Provides New Insights into
RT Benzylisoquinoline Alkaloids Metabolism.";
RL Mol. Plant 10:975-989(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OVA16670.1}.
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DR EMBL; MVGT01000481; OVA16670.1; -; Genomic_DNA.
DR STRING; 56857.A0A200R1W7; -.
DR InParanoid; A0A200R1W7; -.
DR OrthoDB; 1384804at2759; -.
DR Proteomes; UP000195402; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03232; ABCG_PDR_domain2; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR PANTHER; PTHR48040; PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1; 1.
DR PANTHER; PTHR48040:SF23; PLEIOTROPIC DRUG RESISTANCE PROTEIN 3-LIKE; 1.
DR Pfam; PF01061; ABC2_membrane; 4.
DR Pfam; PF19055; ABC2_membrane_7; 2.
DR Pfam; PF00005; ABC_tran; 4.
DR Pfam; PF08370; PDR_assoc; 2.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000195402};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 614..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..747
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1247..1265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1285..1305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1326..1348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1360..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1389..1410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1471..1493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2018..2041
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2094..2116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2219..2243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2653..2671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2683..2703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2715..2735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2741..2762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..515
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 923..1176
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1641..1923
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 2307..2560
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 886..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1587..1618
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 892..908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2798 AA; 317093 MW; 0F34BCB439D484C2 CRC64;
MVQLMMMDIE EENNVADKPV AIVMESSSSS SLSSTDQISR SISLRHRAAL SLRSQSFNAV
IIRDCMMMRE QSSSTNDNDD EVQLQWAAIE KLPSIKRLRT SLDLSFNRHH HMTNGGNYGE
SDEEPKMNNI IINNISKLGA SSLESQVYID KLIKHVEEDN RRLLEHLKER MDKVGIKLPT
VEVRYKNLCV EAECKVVHHK SMPSLWNSVK GMFYVIAKIP SCSSQKAKLS ILQGVSGIIK
PSRMTLLLGP PGSGKTTFLK ALAGKLDQSL KVSGEISYNG YSLESFVPQK TAAAYISQYD
LHIPEMTVRE TLDFSARCQG FGGRTEFMME MNRREMEAGT VAQPELDIFM KVRIMHHLQN
GQCGFTTIWT ILGLDICADT MVGDTMRRGI SRGQKRILTT GKSRNIMQFL VFQRCECQLC
CFLTGEMMVG PRKALFMDEI STGLDSSTTF QIVSCIQQLV NITDGTALVS LLQPAPETFD
LFDDIILFAE GKVLYHGPRN HILKFLEDCG FKCPKTKGVA DFLQEVVSRK DQSQYWYYTE
QPYSYVSVDQ FSEKFKAYHL GQKIEEELSK PCEKFQTQKD ALSFTNNSKT KWELFKTCMG
RELLLTKRNS IASVFRLAQL VIIAFIMMSV FLSKRMKMDV VDADHHMGAL FYALTRFAIG
STAELPATAS RLSVFYKERN FKFYPPWAYS IPTYLAKVPF SLVECLIWTS LTYHGIGYSP
EVQKFFYQFL LFFALQQAIT SLFRFIASVC QTDVAATTSA SLSLLMMLLY GGFIIPQPSL
PASMRWGFWV SPMSYAEIGL SVNEFLAPRW QKVISGNSTT AQEALTRHGL NFDRYFYWIS
LGALFGFTIL FNIGFTLALT YGKSPGVSRR VIVSHEKFYQ RKNEDSNIGK HESIKPNSSA
PPTTCTKTGR TEKMVLPFEP LAITFQDVQY FIDTPLEMRK QGVTETRLQL LSDITGEFRP
GVLTALMGIN GSGKTTLMDV FSGRKTNGFI EGEIRVGGYP KVQKTFSRIS AYCEQFDIHT
PQITVEESVA FSAWLRLPSE IDSNTKAEFV KEVLHTIELD GLKDVLVGIP GVSGLSNEQR
KRLTIAVELA SNPSIIFMDE PTSGLDAKAA STVMRAVNNI VNTGRTVVCT IHQPSLDIFE
AFDELILMKK GGQIIYSGPL GHHSSNLIEY FEGIPGLPKM KENYNPATWM LEVTNESFEE
KLGIDFAQLY KEELYFRNRF SCNGWDQFKA CLWKQHLSSW RSPKHRLLRF MCVTFSSLLL
GRLLWQKGKK INNEQDLFNI IRSMFIVLQI VGINDCSSVL PIMATERTVL YREKFARMYS
SWAYSFAKVI IEIPYILLEA VIFVGITYPA IGYYWSVYKV FWYFYATFCK LLYFNYLGML
LVSLSPNVGV AAILANGCYS ILNLFSGFVI PGPDIPKWWL WFYVISPTSW SLNALINSQY
GDINNEILAF GKPKAINAFL KDYFGYHHDK LGFVAIVLAI YPLVFAYLFA LFIGKLNFQR
IEMNKMTADA LKIEIDDDDI SEDEVELQWA AIERLPTFER LRTSLVLDEN GDDYHDVEAM
KARKKQRVVD VTSLKALERK LFIDRLINHV EEDNRRLLQK IKERLDKADV ELPKVEMRYK
NLCVDAVCET VQGKALPTLW NSFKNLFSVF TKIYGCETQE TKISILKDAN GVIKPSRMTL
LLGPPGCGKT TFLLALAGKL NQNKSITGEI SYNGYKLEEF IPQETSAYIS QYNLHIPEMT
VRETLDFSAH CQGVGSRTGM MTEVIRKEKQ AGTVPESDID IYMKAISIEG LERTLQTDYI
LKILGLDVCA DTLVGDALRR GISGGQKKRL TTGEMIVGPK KAFLMDEIST GLDSSTTFQV
VSCIQQFVHI TDATVVVSLL QPASETFDLF DDIILMAEGK IVYHGPRSHV LEFFEHCGFR
CPERKGVADF LQEVISERDQ EQYWYHTEQS YSYVTVDQLL KNFKEYSIGQ KLDEELSEPY
EKSQCHKNAI SFSIHSMSKW ELFRACFARE LLLMKRNLFL YLFKFAQLSI IALITMTLFL
RTRMEVDALH ADYYIGSLLN ALIRIVTNGI PELSMTFSRL PVFYKQRNVY FYPAWAYTIP
AVILKLPLSL VESFMWTALT YYGIGYSPEF ERFCRHFLIL FALHQTTTSL FRFLASVYQI
GDSLPAWLNW GFWLSPMTHG AIGLSGNEFL APRWQKVTFE NTTIGHETLT SHGLDFAGYF
YWISLGALFA FTLLFNIGFT LALTYSRPAQ MPRVLISHEK ISQLPGREDC GSNEHLNNKL
DSTISTISDG EARKTGKMIL PFEPIAMTFR DLHYFVDTPK EMRKKGFPLA KLQLLGGITG
TFRPGALTAL MGVTGAGKTT LLDVLSGRKT TGIIKGDIRI GGYPKVQETF ARISGYCEQN
DIHSPQITVS ESVIYSAWLR LPPEIDPDTK TEFVREVLET IELDRIKDAL VGIPGVSGLS
TEQRKRLTIA VELVSNPSII FMDEPTSGLD ARAAAIVMRA VKNVVDIGRT VVCTIHQPSI
DIFEAFDELI LMKKGGQIIY SGLLGEHSSK LIEYFECIPG LPKIKSNYNP ATWMLEVTST
SVEAKLGIDF AHIYRTSPLC RESEELVEQL SKPPTGSRQL HFPSSFPRNW WGQFSACLWK
QNLSYWRNPA YNLMRLMFTT ILAVLFGLLL WQKGKKINDE QDLFSMVGIT FVAIIFLGMN
NCSTVLPCVA TERTVLYREQ FAGMYSSWAY SAALVTTEIP YLFLQAVIYV VITYPAIGYY
WVAADVIKPK CQDSIHMRSF LLHPSQPLRR VFITSSGI
//
