ID A0A210PNL5_MIZYE Unreviewed; 910 AA.
AC A0A210PNL5;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glutamate receptor {ECO:0000313|EMBL:OWF38063.1};
GN ORFNames=KP79_PYT12818 {ECO:0000313|EMBL:OWF38063.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF38063.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF38063.1}.
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DR EMBL; NEDP02005574; OWF38063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210PNL5; -.
DR STRING; 6573.A0A210PNL5; -.
DR EnsemblMetazoa; XM_021523452.1; XP_021379127.1; LOC110466732.
DR OrthoDB; 511851at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR CDD; cd06380; PBP1_iGluR_AMPA; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF600; GLUTAMATE RECEPTOR 1-RELATED; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:OWF38063.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..910
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012849278"
FT TRANSMEM 554..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 416..792
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 426..500
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 910 AA; 102763 MW; 11C03E520A9C1614 CRC64;
MRSCSVISYM LYLFFGTVLL KTTSASRTYN ISALFDPRAE ELRNEFEMEI KRIQVDDRPG
TYLDPKFREL DITDSFEVSN AICEQLENGV LAFVGMSKVC ALSTIQSYSD TFKAPFITLS
MPQNSTSADP YQLYMRPHYI DGLVDVIVNY GWKELFYIYD TDEGLIRLQQ LFQAFNVREY
ELIDINVKRV RDAHESYMLL RDIYGTVKDT NLRILLDITT DEARTLIMNV RNDRDMINNR
FHFLLADLDI NDMGDEPLRS GINVTGFQLN ATEDGPAKSK DRDIYANILN KKITLEKALV
LDAVRLIHKA SKKLNPDLYD QGLTGMKCRV GDANVRRVPG KTFMRALRNT TYNGFTGTVQ
FDDRGFRKKF KLPLIQTTMN MERAKVGEYT REGGLTQHDP KVVPHINIKN APQNETKIVT
TVLDPPYVMI KNDALKDPEA HMSREVRCGK HKFEGFCIDL AAKIAEYVNF TYDICLVNDL
HYGTMLENGT WNGMIGELTR READLAIAPI TISSARERVV DFTKPFMSLG ISIMIKKPSN
AKAHVFSFMD PLSYEIWMCI LFAYVGVSVV LFLVSRFSPT EWHVEDDSSI TNDFTISNSL
WYSLGAFMQQ GCDISPKAIS GRVVGSVWWF FTLIIISSYT ANLAAFLTVE RMNTPIESAE
DLAKQTNIQY GVLNAGTTKD FFKYSKVAIY ERMWAYMTSA NPSVFVNNNT AGIGRVRSSN
GKYAYLVEST MNEYTNMRKP CDTMKVGTNL DSKGYGIATP VGSPLRDRLT LAVLHFRESG
ELQQLKKKWW DDRSECPSPG TASDGGQTAL TLNNVAGIFY ILISGLTLAI LIAGCEFIYK
SVVDSKKSKT SFGSVLRCKA RLSFRGSFDK EASDAGVPIR KTMSTYTYTG PTQLPGFDPY
PDTNNTHTQV
//
