ID A0A210PVT7_MIZYE Unreviewed; 897 AA.
AC A0A210PVT7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4 {ECO:0000313|EMBL:OWF40608.1};
GN ORFNames=KP79_PYT04485 {ECO:0000313|EMBL:OWF40608.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF40608.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SIMILARITY: Belongs to the Toll-like receptor family.
CC {ECO:0000256|ARBA:ARBA00009634}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF40608.1}.
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DR EMBL; NEDP02005459; OWF40608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210PVT7; -.
DR STRING; 6573.A0A210PVT7; -.
DR EnsemblMetazoa; XM_021518275.1; XP_021373950.1; LOC110463573.
DR EnsemblMetazoa; XM_021518276.1; XP_021373951.1; LOC110463573.
DR OrthoDB; 2967120at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR PANTHER; PTHR24373:SF275; VASORIN; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF01582; TIR; 1.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:OWF40608.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..897
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012035579"
FT TRANSMEM 690..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 748..875
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 897 AA; 102743 MW; 8A6849ABB9157582 CRC64;
MPCSSLPYVL FAINVFLMSP IRGERENCSA PCSCTYKGNT IDGLDCSNLK WNNIPPKFNF
PSSAEHFSIA NNRFTVLHNG TFRNLSKLQS LDISHNRLAV LGYSCFEGLE SLLTLNISYN
NLKMTTNVYA PGIFRYLENL KVLNIHGNIK QSTVDQNYPD VALSDLEFLE ELTMDGLTRV
IFGEGFRKLR FLTSLDMSVR DDESSCVLLD VLNITFSSLS NSTLSVLKLA QCNIYHIAPG
AFAMLKHLTE LDLSENDRLG FGGMKNASFG LHLTNIQILR LNRINRHIDP FTLKQKDFVY
FNTTTIKTLT LDSNIITKIE NGVIDLLPMS LVFLTFRNNY LTDVHFLVNL VRLNNLLVFD
MSYQLNYHIR VKTDHESQNV RPTPLLYKGR RVEKEEKSDE KYIIPLSKYV VRSQQVVKEP
NEYQYNLLRS NSHQTDDVLR LPVNVQKIFG SNLKLNPLTA PPVTFDSNNS LEYLDLSSNG
LHAWYGKWSG LHSLRFLNIS FNAMFRLAPD TFGDMANLHT LLLNGNRLGI TIMQDTQFLT
FSNQTKLTYL NLSDNGLTDL PKFIFAKQIN LEKLDLQQNF LSAISFRMES LKRMREINLS
NNTIIDLTRV NMEEMDHLAK QSNFIIVLTG NPLKCTCDQL EQLRWMMVTE VVFRNLKHYK
CKASNGSVVS LARLDDMIGQ MDIDCIAGEV IIICVAVFCG LCLLLSLPAL AYYKRSRLIY
LFSVGRKFIS PIGKNIQQSE DEANDEHLKF TVYLSLEPSR PVNDFVSRFQ VYMQNKGVSM
CIPELDLIGG GKETVDIVKA MNNSTCILAL INNDYMTSFH RLFEFEVAVT EGIQNQFNNL
IVVLLEDLDN NHMQLNDFVS MYCRENHYFE VRRSRGNLFG ELENEIIRYK EFTKKRP
//
