ID A0A210Q0T1_MIZYE Unreviewed; 882 AA.
AC A0A210Q0T1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RING finger protein nhl-1 {ECO:0000313|EMBL:OWF42353.1};
GN ORFNames=KP79_PYT19439 {ECO:0000313|EMBL:OWF42353.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF42353.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF42353.1}.
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DR EMBL; NEDP02005295; OWF42353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q0T1; -.
DR EnsemblMetazoa; XM_021514566.1; XP_021370241.1; LOC110461197.
DR EnsemblMetazoa; XM_021514567.1; XP_021370242.1; LOC110461197.
DR OrthoDB; 2905462at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd14954; NHL_TRIM71_like; 1.
DR CDD; cd16524; RING-HC_NHL-1-like; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24104; E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED; 1.
DR PANTHER; PTHR24104:SF8; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01436; NHL; 6.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51125; NHL; 6.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}; Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 21..63
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 148..188
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 609..650
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 654..697
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 704..744
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 751..791
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 795..838
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 845..882
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REGION 93..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 96515 MW; DC52368CC4A62F5C CRC64;
MEEDPQELSY SSEHIEQLLQ CAICLDRFKQ PKLLPCQHTF CETPCLENLV NFLSRSIKCP
ECRAEHRVPY QGVSSFPNNL TIRNFLEIPT KRIRRTSGGS GGDGAGGSTV ASGSTSAAGG
SGGACASSVG GQYINAVAQD REPPTAAASR SGCTICTRET TLSRCAHCDQ VVCDACKRSH
MDHIKLDVAR LVGQIRRGIP HMSDAVNHME IKIEALRQRS ESGKAEITEI IEKYIAELRS
RQRLLHSEVE MFLLGEVRAL RMHQENLEVE MASIASFCDT NESTLSRSQQ NTSDEGIVED
KKQCVEYMEL LRSYELGNYP LPRERSLQFY MEENRLSNVI AGFGEIVTNN SQSTSESQSS
ASSRDSSPVV SLTNVVTTTP SLTTTTTPST STANSGPMNT DRALALIRGG HHLSAFTTPS
PAPDSDSEAR SSPLPRRTLQ ERRRGHMSDT RIAGLMAGGG GGGGSGGGSS SPRTSTASAL
RERRLNRSLS TGASLFTPVS SLTNQPSTSI QEEPSASPSP RPRRAERSNT FSREESNTAS
EVVPQTSRVS SADARPRARP PVRFDVGLDD NGDQNELPGL ELLSFSDNES CVVTTATNNY
QDKGRAIIRF GQRGTDFMQF TWPRGVATTR ENNILVADSS NHRVQVFDSV GKFVKVFGSY
GQGEGEFDCL SGIAVNSFGQ VIISDRYNHR IQVYNRHCEF ELAFGTEGSD QGQMLNPWGV
ACDNMGFIYV CDKENHRVQV FQTNGRFVRM FGALGHRSGL FENPHFVAIS PDNKIFVSDS
SNHRVQVFSM YGDFLFAFGC PGTMEGQMRF PKGIAIDDQG FVVVADSGNN RVQVFRGNGR
FYCMFGSYGS DNGQFKGIEG VAILGNGNII ISDRENHRIQ IF
//
