ID A0A210Q1D1_MIZYE Unreviewed; 555 AA.
AC A0A210Q1D1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Pleckstrin homology domain-containing family A member 8 {ECO:0000256|ARBA:ARBA00016588};
GN ORFNames=KP79_PYT02041 {ECO:0000313|EMBL:OWF42560.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF42560.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane
CC {ECO:0000256|ARBA:ARBA00004198}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF42560.1}.
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DR EMBL; NEDP02005260; OWF42560.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q1D1; -.
DR STRING; 6573.A0A210Q1D1; -.
DR EnsemblMetazoa; XM_021514115.1; XP_021369790.1; LOC110460907.
DR OrthoDB; 642641at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0120013; F:lipid transfer activity; IEA:InterPro.
DR CDD; cd01247; PH_FAPP1_FAPP2; 1.
DR Gene3D; 1.10.3520.10; Glycolipid transfer protein; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR036497; GLTP_sf.
DR InterPro; IPR014830; Glycolipid_transfer_prot_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10219; GLYCOLIPID TRANSFER PROTEIN-RELATED; 1.
DR PANTHER; PTHR10219:SF43; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8; 1.
DR Pfam; PF08718; GLTP; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF110004; Glycolipid transfer protein, GLTP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..96
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 194..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 62178 MW; 7475B9B2995B7E1B CRC64;
MATMEGLLWK WTNYMSGWQP RWFVLDNGVL SYYKSQEDVI NGCKGSLQMS VCDISVHSTD
HTRLDLIIPH EQHFYIKASS PHERQRWLVA MGTCKASLTN GRPSEEMGEI SPDIVRTKKS
ELRLYCDLLM QQVHSVKSAI QESQPEVKKL DEATSLLGAT CDTFIQTLDD CMKIANASIA
YETSPKPVRD VQLVLPQKTV KKGERLSTSG RPSSAESRSV RTSPLPRDGL PSFPKSSNRR
RTASENSHSD QSLSDHSMDA NRDHTESDNR NSSTRLSVTM ETNSFSKSLT SGSVSKTNVN
SGLDHSSKRT ENGVTSLEKS SGKSLSSTSI NSEEEFKDAI DAKVPTFFST MEPSFMDIKL
EEDGGIPVQP FLGSCRSLVP IFDKFNATTF APVKMDFQGN IRKIQQKYST KPSDFTTLQR
MVLFEMRSQQ HHLSSSATVA LLWMKRGLEF IRAIFQEMLE GQPDLCLAVN NAYSRTLKPF
HGWVVRGVFA VAVKALPYKE VFITQLRATG HPGEGSIFLQ SLMADLDSYC TALDEVIRIL
KDFYKSHSLD NDEQI
//
