ID A0A210Q360_MIZYE Unreviewed; 1343 AA.
AC A0A210Q360;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Transient receptor potential cation channel subfamily M member 3 {ECO:0000313|EMBL:OWF43174.1};
GN ORFNames=KP79_PYT15175 {ECO:0000313|EMBL:OWF43174.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF43174.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF43174.1}.
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DR EMBL; NEDP02005156; OWF43174.1; -; Genomic_DNA.
DR STRING; 6573.A0A210Q360; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR Gene3D; 1.20.5.1010; TRPM, tetramerisation domain; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR041491; TRPM_SLOG.
DR InterPro; IPR032415; TRPM_tetra.
DR InterPro; IPR037162; TRPM_tetra_sf.
DR PANTHER; PTHR13800:SF1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM; 1.
DR PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF18139; LSDAT_euk; 1.
DR Pfam; PF16519; TRPM_tetra; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:OWF43174.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 577..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 838..857
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..117
FT /note="TRPM SLOG"
FT /evidence="ECO:0000259|Pfam:PF18139"
FT DOMAIN 580..815
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 907..960
FT /note="TRPM tetramerisation"
FT /evidence="ECO:0000259|Pfam:PF16519"
FT REGION 1001..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1063..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1144..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1205..1225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1148..1165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1343 AA; 153594 MW; 389A17C07C3F6AD9 CRC64;
MRISAPKSGC KLLSKSYVFS ASGVKGRGVP VICVVLEGGA NTIRSVLEYV TDSPPVPVVV
CDGSGRAADL LAFTHKYTLE DGTMPESLRD QLILTIQKTF QYSQEQAEKL FIELMLCIKK
KELITVFRMG EGAQDIDLAI LTALLKGTNA SAPDQLSLAL TWDRVDIARS HIFVYGQEWP
EGSLEQAMMD ALINDRVDFV KLLLENGVSM QTFLTIQRLE ELYNTRHGPS NTLRYLVRDI
KKHVPSHYRY NLIDIGAVIE HLMDGAFRAS YCRKRFRQKY NAIKRNGVAG NMGNLVTTLP
LFLDTKEAQE LFPYPFHDLM IWAVLMKRQK MALFMWQHGE EAMAKALMAC KLYKAMSHEA
DSDDLEVDIS DELRSYAKEF QVLALGLLEH CYKIDDDYTQ QLLTYELKNF SDQTCLSLAV
AANHREFVAH TCCQILLNDM WMGGLQMRKN SSLKVIMGIL IPPYILALEF KSKEELQLMP
QTMEEHLDEL ENQASEEGDL SFSEDINEDH VNENLYIDDV NVETSFHSSS QGFPRENGSI
HNESNQEYSQ FTIKKKKSPL RLGKRIYEFY NAPITKFWFY TMAYIGFLIC YTYVVLVKTS
PEPRWQEYLV MSYMFTLAIE KIRQVIASEP VKIRVKLRVH FSQLWNVWDS IGVALFTVAV
LIRHVQDTTN NVRVLYTINI VFWYIRILEI LSVNKYLGPY VKIIGKLLRD MSYFIIILLI
VLMSFGIVRQ AIHFQNEEPS FKLVRNMFFY PYWMIYGELF ADEIDTCTDT ERHPEGCTYG
SWVAPALMCV YLLVANILLV NLLIARFNAT FIKNNANSRE IWKFQRYQLI INYELRPILP
PPLLFFSHIF LAFKFMIRRC KGKRDLFDNG LKLFLSLDDT EKLHDFEEEC IEDYFREKEH
QFQSSNEERI RIINERVENM TLRMDDVNQK ENSIKLSLQT VEYRLSKLEE ISIQSADILN
SMRNFMARGV RHISASSGTS SHGRLGSQDS IVEVADLHMY DTPAKTEQEA TTSRGTGPDR
TSESSITTPD ANATMRSIPS PLLVHSKKPV KEEHMHRYTD FTKPITLQRS GSGHRSMDRS
HSQKSRTPLP RLSENSPEAK ITEPIVPKEI SLQQRRKGGP NTTMTTGQMT TDGMIEDMSD
EEQQEISSKD PPIITTSLSS SPVRSSGHAA TAMYSVPSSM VAQLTPILTS LRSEYTTITD
EIDTSCMMDK SPPGSPSTAG AFFDGKFDNR KKNSIKMLNE NALLKQAEEV GHKRMEKVIR
HRLRQISLDE NDSISDIAKL VVSEMNLTEE DPEEQSGQED EPEVNHSDHH GSAESVIMGH
LTTDMVEIRI RRASTEDKSD MTL
//
