ID A0A210Q3U0_MIZYE Unreviewed; 1017 AA.
AC A0A210Q3U0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Zinc transporter ZIP4 {ECO:0000313|EMBL:OWF43428.1};
GN ORFNames=KP79_PYT24176 {ECO:0000313|EMBL:OWF43428.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF43428.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF43428.1}.
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DR EMBL; NEDP02005106; OWF43428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q3U0; -.
DR EnsemblMetazoa; XM_021512185.1; XP_021367860.1; LOC110459765.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR12191; SOLUTE CARRIER FAMILY 39; 1.
DR PANTHER; PTHR12191:SF30; ZINC TRANSPORTER ZIP4 N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1017
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013030053"
FT TRANSMEM 693..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 723..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 763..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 926..948
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 954..977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 989..1009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 211..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..402
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1017 AA; 114749 MW; 7DFB1D1365B7D266 CRC64;
MLVLIYAGLS AIVIGQTEAN RKVSCTFEGL KTFIAIGYHL TEHNHSDPST LLDKMIRVML
LRMNCEKRYK AMLFRKMHEH HGEHWINTLP AAYDEYLNKS HVKKFVTKIT RSDAVTATTL
NAMAATILKV AINFECFVSR TLFEPSEDFT NDFLLENNYE HTLKMINQHY VRHMNSDKMD
RMSYVNRLQC LNVKTALGDI QRELKSHGHD QHIHHSAGHN QGNVQPHHID LHGKENDHVR
DVAPVLIHPD DKGNHLNKFK RSYNVIHNEE YAASRNKTDT SFTKSIQDPD MNSNIESVVF
KPVITHYTNV KNSENDGSHQ YNAGKNKQLR AAHHVHNASN TNINTVKEYD TTDFHNNDTH
DDRKYSHYQG TRGSMHNNSN SNKDTVKHKH VHHERHPTHS RQHTHTQPSD AQTIQATAAH
VTVGHNQAHN HNQQSNQAGR PPNQQQMLST HKTLTPRSTS YERSTPTQKS TPAPQATLNQ
QPPPDHPMRP EERPPSENHI NCLSTENRWS KPRHLHPLQR EHIDSFYANI ALAMIKGYKL
QDNDLPCPGA FLHDMFDKYG EKGLLNSAGL KRIMAVKKPL SGHLEHAHNS QKHDHHENVV
HAHKHDSQIN TTCEVKRRRI TEGYKQFVNV EAIAPKVMPC LSKDDLKTMF HVKGGITMTT
FLDMCPVILQ QLVSDACANK STIVQQTTPL EKYGLSTLCV FIISLCSFAG AVFVKCAHSV
NRVYVMAGLL ALSVGCLLGD AIIHLLPHVL AQGHHGDHDD SNTVYKMCGA LISVYSFFLM
ELFFRHSHNH KNDADMDIEI SRDTQSCTST TSAVSDIQLI DMRKNNLRTP KTENKTRVWQ
KVSTNSADAQ PEEETKQQSS GSLKWMVLIG EMVHNFADGM AIGASFAESL TEGLSTSLAV
FCHELPHELG DFAVLLSTGM SVKKALLLNF ASSLTAFIGL YIGVAIGSND EARLWILSFG
AGMFVYIALA TLMPELVGYF NCYTNIKMFL SLNFGLLLGF LFMLLLAVFE DDIRLIL
//
