ID A0A210Q697_MIZYE Unreviewed; 542 AA.
AC A0A210Q697;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Parafibromin {ECO:0000313|EMBL:OWF44257.1};
GN ORFNames=KP79_PYT03860 {ECO:0000313|EMBL:OWF44257.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF44257.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC73 family.
CC {ECO:0000256|ARBA:ARBA00010427}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF44257.1}.
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DR EMBL; NEDP02004840; OWF44257.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q697; -.
DR STRING; 6573.A0A210Q697; -.
DR EnsemblMetazoa; XM_021510406.1; XP_021366081.1; LOC110458622.
DR OrthoDB; 180759at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016593; C:Cdc73/Paf1 complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.40.50.11990; RNA polymerase II accessory factor, Cdc73 C-terminal domain; 1.
DR InterPro; IPR007852; Cdc73/Parafibromin.
DR InterPro; IPR031336; CDC73_C.
DR InterPro; IPR038103; CDC73_C_sf.
DR InterPro; IPR032041; Cdc73_N.
DR PANTHER; PTHR12466; CDC73 DOMAIN PROTEIN; 1.
DR PANTHER; PTHR12466:SF8; PARAFIBROMIN; 1.
DR Pfam; PF05179; CDC73_C; 1.
DR Pfam; PF16050; CDC73_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 1..295
FT /note="Paf1 complex subunit Cdc73 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16050"
FT DOMAIN 379..531
FT /note="Cell division control protein 73 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05179"
FT REGION 104..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 318..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 542 AA; 61846 MW; BDCF6AD20756FC3A CRC64;
MADVLSLVRQ YNINKKEIIE KDDQVIFGEL AWPSNVKTNY VVWGTGKDGI VKEYYTLDCI
LFLLRNVHLQ HPLYVREAAA AEVPVVRRPD RKDLLSYLNG ETTSSASIDK SAPLEIPLQR
PPQVKRGGED SGEADKKKKP RLEDEQVQHA KMNWIHKIDA TRETSALQQI SRSSLPEAMP
LEKIAAIKAK RLAKKRTMIK VDDEVAPGAL EQRSFVEAEV DVTRDIVSRE RLWRTRTSIL
QSNGKTFAAN VFGILQSIKA REEGKEKHHT EPHTPSVPQQ RVPPVAAYSR YDQERFKGKE
ETEGFKIDTM GTYHGKTLKF VTEGGGANQK KIEEREPRRH AAPQQNHVSH HPVQPSTPVT
PGSRPISQAR PPPNQKKGSR TPIIIIPAAT TSIITMFNAK DILQDHRFVS TEEKKAQGTK
RDNEVLIQRR KAGNLTVPYR IIDNPLKLSP DDWDRVVAVF VQGPAWQFKG WPWDGVPVDI
FSRIKAFHLK WAELPVDTNV KKWDVCVVNL NRNKRHLDRA NLQQVWEILD KYMAKHKPHL
RH
//
