ID A0A210Q923_MIZYE Unreviewed; 450 AA.
AC A0A210Q923;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|EMBL:OWF45234.1};
GN ORFNames=KP79_PYT11259 {ECO:0000313|EMBL:OWF45234.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF45234.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MiT/TFE family.
CC {ECO:0000256|ARBA:ARBA00008289}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF45234.1}.
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DR EMBL; NEDP02004538; OWF45234.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q923; -.
DR SMR; A0A210Q923; -.
DR STRING; 6573.A0A210Q923; -.
DR EnsemblMetazoa; XM_021508501.1; XP_021364176.1; LOC110457295.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11397; bHLHzip_MITF_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR031867; MiT/TFE_N.
DR PANTHER; PTHR45776; MIP04163P; 1.
DR PANTHER; PTHR45776:SF2; MIP04163P; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF15951; MITF_TFEB_C_3_N; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 269..322
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 420..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 315..349
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 450 AA; 50486 MW; 62691BAB0C5B21E1 CRC64;
MQDSGIEFDL ISQIEADALL DDDNFYALKS KVIVGSPKVE LKHVNMPLRA NLRQQLQKAQ
LAEEVEREKD TSLLSQSHRH VSTKPQVIQV PMSSSLNSGE VPVHILKVQT QLKNPTLFHV
QENKKRQIQA FLSKSLDSPG AIQSLPNIST MTINTNELGL SGSAPVDPDS PLSVGLSSCA
TSVSDMDNLL SDILSLEPVD VTVDHDLNSI EPSLTHMSST LPQSNLVNNV HELTGNTESS
NSCPAAFRRA ETPPFMSEEE SRMWAKDRQK KDNHNMIERR RRFNINDRIK ELGTLLPKTI
DPDLRQNKGT ILKASVDYIR RLKKDQERNR QLEDRQRGLE QTNRKMLLRI QQLELLMQAQ
GMTSGMQDDI DNFIMQSNAS HQIQQQQNIS MTLTNTQNLS PAVTLAPLET HSQTHHLLDD
LMDDTSPLGI DPMLSSQPVS PNDMDDSEEL
//
