ID A0A210Q9C8_MIZYE Unreviewed; 3082 AA.
AC A0A210Q9C8;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Lysine-specific demethylase 3B {ECO:0000313|EMBL:OWF45352.1};
GN ORFNames=KP79_PYT17175 {ECO:0000313|EMBL:OWF45352.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF45352.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF45352.1}.
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DR EMBL; NEDP02004518; OWF45352.1; -; Genomic_DNA.
DR STRING; 6573.A0A210Q9C8; -.
DR EnsemblMetazoa; XM_021508271.1; XP_021363946.1; LOC110457157.
DR OrthoDB; 3473445at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549:SF11; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A; 1.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:OWF45352.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transferase {ECO:0000313|EMBL:OWF45352.1}.
FT DOMAIN 2837..3044
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 255..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1000..1047
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1069..1116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1171..1228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1421..1443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1480..1545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1587..1619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1642..1848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1861..2173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2397..2424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2502..2646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..502
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1069..1083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1091..1107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1338..1352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1353..1379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1426..1443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1480..1520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1642..1687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1688..1730
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1731..1813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1821..1848
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1881..1904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1956..2001
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2038..2054
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2066..2082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2096..2173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2504..2522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2523..2540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2555..2577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2588..2615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2632..2646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3082 AA; 345516 MW; DB475F640987DFAD CRC64;
MAYKSREEIA GKRFLSVRCS GKLKLNKIVD WEWRSGVVRA VTGKDTSNPD VSVLVEFDDR
HWQRREWVRI HEIFQLFLVE HTVVWAERAD PENSEQPISW PGLNFRTIVD KACLNSSKKK
PIEFLADKFL GLVDDRSLKS HSDGDENKAQ TLRRFPQAGQ AIKAWHDYQD GQKILLTTPS
VLVGYRVEVY RAEGTTQWYT AVIQSYNHTS KTLSVTDDTV LEEHNEDPAL IQMRLIDDGV
VDSILRGVEV GIGPRRTRQT NKDKDLQSTS NTFPRGTPKS TEQTGNSTNK TPSRTSKTRL
LTPQNSSQSQ QGNTSGNNTT TPDSEKDKTN VRTKPTRERK RKTDEESDWR PSTPVQPTAP
STGKRSKPKD TNKQGLTSEE KKEKTLSPLK RARSSDGRRS TGNQDTTPPV SSAPTGNKRP
KSFDRKPTLQ LKKCDTNLSL DKSSVVSRKR QTENTKKLRN RSEPRTTPRS VNSKERRQIS
PSPVKTELTR KASERESRKS KVTGKSGLTS PAAVSKRWNV DQQHCDVKKA SDNVETSKCD
SETSVVKSAT DSDLSPVTEP TVNKDDDTGT ESSASGSKDV LTHSAVSDSV VVPCDTEVTR
ECTGSESEAV ADDSSHLTVE TLSTDTDDNM HFMKRRLLAG NNSSESSSNP PSNSLAGIDV
NRSLTDQITK LARTEKLALH GEDTGSSINQ TKSVSPHSES SDTVVLVKDT RSDSVPVKEN
TLFNYGNSTQ IPNDRSSSRT SEHSSYSGYG DDRRPSSRLD DLRTSSKNSP ASSPLIIDRT
EPVLPYRDPE LMRKNPVQSN VQSMLGPPHK SSTYPGVHNP IPSAPPSGSL PTTTSFPTHP
LPRTHVLPSM SYHPMGAAAA AQLGLSPGLG QLDHATLAAI QQQQLALQYS NSLLLQRSAG
YPPPANLTMA QLELLWQQKY PSVPVPPQWM LASKQEDLLR DIFSMKEREL ERYERDRIER
ERLERERMDR LEREKIERDR QIERERQERE RIERERIERE KMERERAERE RAERERMEKE
HLEREREREL ERKRREHEHE QRQERERILK ESADTLAAVD DHFQQSLRLA KQRAQQSGMI
WAPPSITLGT GKSGPPKSEQ QSPSSYHYGH GDKADKQEII KSMEEKVKQE REREEMRHLS
FNTEMLRRHE IMRQQELFAA VKQEEFMKER QKALAAEHQK SDQKLEKVSS SRSSDAKPHN
YQQAQGFKGY PVSSISSGSG SGVKQEPNYS LYGYQPFQHT YISPEQLHLH GLAAAEKQSE
EKMNIDSKHG SACSTSPKRP KTGVPPPLIK DIKSHSSVIV ENKGKDSGKS ASPRPAHSHY
SSTIPMPPST SPRPQPKPAH TPDRHHHDRP RSALASSSPS AGSYHHDLSG SMDLSSSGSH
VSLSSLKVEN KHITSNSHSP LSQGLNHQQL ASAMLGQPVD YHRGKGAVSS TSSGGSSAPS
SNSHYMSAAI AQPPVSLPGR SLAYSYSLIQ QGLVPNPIYS QSTVKSMPST HSDQQKGNSS
ASIPTPTSQS SSSSTGGQQG VKRKVIKDGP QRKRQKAENV ANSALNVPVT TPQILTNHSP
YTTTSSTTCT TVSSALSNVT MTTKSAMNTI SSPSSSFSSS TLSTSSFMSS PSSLAAGSQT
ASGFMDSFKS FVENAVQNAF LQDQDLNKPS KSSNSGSSNN SKLHSTTTTT TTTTETKQQQ
QQQSWHPIGK SPPPPPAQVG QTPPPQPVLH HSPQPQPQPQ SQPQPQSQPQ PQSQPKSQNQ
RRKSDPLQLS SCLDDSHSQT LSSSSSSISS HTALMETINR VANGQIDTDS DTLSAPSPPP
HVKSDSTSPH KSGNAPKLKK AWLQRHSDED KELKNSPVPH GDSREQKAEI VRNCYVNCSY
ISPSKEGGSR SPISALRING NLKDHSISND ESTTSASETE SAQNPEVPGK KRQKKRSSTN
KKQRQEQQES EAMVESIPNP NPSPNTNPTP VTASKKKSKK NKESKDSAKS KESSEDERSN
GSVVKKLKLE PKSENKLELK LEPEVTNGSG IPPTSPPVPT SAAPPIKKEK KETKHASYAS
SDSQQASNSE ANDGPKPMDI SKPMEAPPSS SLSSSSSSIS SISSKEKKKH KKERQREKER
EKERERERER ERERERDRER ERERDRERER ERDRESEKDK EKDRQRDRSR DRDREKEREK
ERDREREKEQ EARDIEMREM ELEWERESNR GCNSIIPPKE VDFIAKNNGS SFNKPLVKAT
VATLKRTCQP FLQDGSCSEV TPKLMKCREC KMTPTQRSKK LPNIFCRFYA FRRLRYSQKG
FLTIAGFSEL SDAEYDDIEP WLPHTPVMEP KMDIETSKYV VAKIGDRFCE LVEQEREARS
WAGEEAKIAW KRAVTGVREM CDVCDTTLFN MHWVCHKCGF VVCLDCYKVR MKALKHEEDD
DEEEEEKERD DDEDHTPPGE DQRRWLTCSS NRQQHEVDKL MLTQIIPRDA LWEVGRQIHE
IRNKWDIPSK CSCDKTMKYP PKNGLTQKYL HALNHISNEK NRKMVNGVGD DHKSHKGNRK
HDSQAVNGNV KSSLGGYSPD SSSPLRMLAD VASMDSENSR ERSESPYNKR RGETDKYGKG
YNPITEPVSP CGQGNVGESE SDKKGPTSCS TLRELLTKTA GKVKSGGESN KKPAKSKNNT
SSTLDDIIQS VVEKQLPRDE NSQPIKLMHY IPRSGYSGMI ACDTPILVHN LTETSVLYPD
VPHSWLCDGR LLRLHDPKHR GNFKIFQEQM KRGQPVLVSG VDNCLNKVLW SPKTFSKEFG
KHKNDLVNTR NGCLIVGHPM ATFWEGFDRI SERLVDDEGD PILLKLKDWP PGDDFSDLMP
QHFEDLMQAL PLPEYTHRQG RLNLASRLPD FLVRPDLGPK MYNAYGSALH PEEGTTNLHL
DVSDAVNVMV YVGIPEDDTG GRSFYENAAL QAIDEAGCDM ITKRRVREVQ EVPGAMWQIW
DARDADKMRD FLNKVAKERG EVIEQHHDPI HDQSWYLDED LRDRLYKEYG VLGYTIVQCA
GDAIFIPAGA PHQVRNLHSC IKVAEDFVSP EHLNHCFSLT QEFRLLSDTH ANHEDKLQVK
NIVYHAVKDA IAVLNEASRD DE
//
