ID A0A210Q9M5_MIZYE Unreviewed; 798 AA.
AC A0A210Q9M5;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|EMBL:OWF45431.1};
GN ORFNames=KP79_PYT20956 {ECO:0000313|EMBL:OWF45431.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF45431.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF45431.1}.
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DR EMBL; NEDP02004512; OWF45431.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210Q9M5; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..310
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 407..595
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 674..792
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
SQ SEQUENCE 798 AA; 90588 MW; 11F1BDA04B1BC824 CRC64;
MSTISVLGDE DFDKWIGKEK RMPTKGKYIA GKQVSRWDAE SEKVDIEYKN LDNASTSKLS
FFSGQKGCAL KLLLLAACLA VGMIVGYIIR RNVHDVFLPP SHKETTLHSS NQEIQDYDDN
LRLMIQQDLN DANNFDDHIR KVTEFVHLSG VGYTNRFIKY VRDMWGTFRF DSIDIRKYGV
TLSYPNYTNP NSIIVRSRNS TVILESHSNM SNVHPEYMPF NAFSPALAGK LVYANYGTKA
DFKQLSLLHV NVTGKLVIIK YGQIHAANKV RHAENNNASG VIFYSDPVDF AHNQSYLAPH
TWWLPGWAIQ LYHVRYNLIG DPLTPGYAAI NGVYRTPPSS DCYPKIPSQP ISYNDAAELM
RDMRGQIAPN KWFGGLNITY RLGPEYLNDR TVELTVNNKD DKRNISNLIA VIEGKYEKDK
YIIVGAHIDS WTKGAVDAGS GYAVIWELAR AFTSKVEKGW RPRRSILFAL WDATKYGHIG
SFEWVQEYEK QLLTGAVAYI NLDAVIRGNY SFYAEASPLL YSVIKTAAGQ VPCVDPDYHD
MSVLQMWTKK FPDLTNSSQP RIYPLEGDSD HSPFYYYLGV PSFSPAYTFN VKLYKNLPTF
PAYSTLEDTI NYLQVFIDPK MELHETVSKV VSDVILRLAD SAIIPLDTQN YISIFENGKT
YLQTLKSVFV VANVNLDTLI ARIDDFSKTV FTFSSNITNL DVSKLNEYHL HHLNHKLVQV
PRVFIIPEGL PGQPQYRNIL MSPHPEDLNS QQVFPGIAAA LKDALNDQNW LPMKKQISYL
LIALRQATDL LKRSSRVS
//
