ID A0A210QB47_MIZYE Unreviewed; 805 AA.
AC A0A210QB47;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU000672};
DE EC=1.4.3.- {ECO:0000256|RuleBase:RU000672};
GN ORFNames=KP79_PYT15397 {ECO:0000313|EMBL:OWF45958.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF45958.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- COFACTOR:
CC Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC Evidence={ECO:0000256|RuleBase:RU000672};
CC Note=Contains 1 topaquinone per subunit.
CC {ECO:0000256|RuleBase:RU000672};
CC -!- PTM: Topaquinone (TPQ) is generated by copper-dependent autoxidation of
CC a specific tyrosyl residue. {ECO:0000256|RuleBase:RU000672}.
CC -!- SIMILARITY: Belongs to the copper/topaquinone oxidase family.
CC {ECO:0000256|ARBA:ARBA00007983, ECO:0000256|RuleBase:RU000672}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF45958.1}.
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DR EMBL; NEDP02004357; OWF45958.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QB47; -.
DR STRING; 6573.A0A210QB47; -.
DR EnsemblMetazoa; XM_021507066.1; XP_021362741.1; LOC110456370.
DR OrthoDB; 2961225at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0008131; F:primary amine oxidase activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR GO; GO:0009308; P:amine metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.450.40; -; 2.
DR Gene3D; 2.70.98.20; Copper amine oxidase, catalytic domain; 1.
DR InterPro; IPR000269; Cu_amine_oxidase.
DR InterPro; IPR015798; Cu_amine_oxidase_C.
DR InterPro; IPR036460; Cu_amine_oxidase_C_sf.
DR InterPro; IPR016182; Cu_amine_oxidase_N-reg.
DR InterPro; IPR015800; Cu_amine_oxidase_N2.
DR PANTHER; PTHR10638:SF20; AMINE OXIDASE; 1.
DR PANTHER; PTHR10638; COPPER AMINE OXIDASE; 1.
DR Pfam; PF01179; Cu_amine_oxid; 1.
DR Pfam; PF02727; Cu_amine_oxidN2; 1.
DR PRINTS; PR00766; CUDAOXIDASE.
DR SUPFAM; SSF49998; Amine oxidase catalytic domain; 1.
DR SUPFAM; SSF54416; Amine oxidase N-terminal region; 2.
DR PROSITE; PS01165; COPPER_AMINE_OXID_2; 1.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|ARBA:ARBA00023008, ECO:0000256|RuleBase:RU000672};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000672};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000672};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW TPQ {ECO:0000256|ARBA:ARBA00022772, ECO:0000256|RuleBase:RU000672};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..168
FT /note="Copper amine oxidase N2-terminal"
FT /evidence="ECO:0000259|Pfam:PF02727"
FT DOMAIN 340..751
FT /note="Copper amine oxidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01179"
SQ SEQUENCE 805 AA; 93572 MW; 747FEBB37D4C5D39 CRC64;
MERIEKQVVT MEKTLDSARR WRSFSVCLLI VIIFLMAAIA TAIVYYELIM RPKKLAHEVI
IQETVDIEEE PTEPSMFRDL TKLEMKRLKK YLYTHRVFNL KYTEPVVISS SFMFLAELHL
PNKSQALDTF NSLHKAPPRE AKVVLFRGDK KIPVIEEYVV GPLANITYHR LLVSKHYQRP
APYLFRPNSQ AEYAEVKKLL VEVDNIIKYV LLESYDASFF NCNRKCLVMQ QWTAVSPAVS
GSDVRKVWYW AHHSTEYYLF NPVDFFILFN LDGKDPSKYH VETIWYNGQS FDTAEHLADA
FTAGTIKKSS MIFPKENQML FSTLNLRGNQ FPNKNMRSPK QVEPDGRRYN RKDRHITYMG
WEFDFRMSTT TGPQLFNIKH MGHRIVYELS LQEMSSFHSG FKPWNRYSDM LYSNSLMGYQ
ARNLVPGADC PPSASFVSAT HWTEHRSEPV TYERAFCLFE QSTGVPLRRH HAYDSVTGRF
YGSLEDIVLV LRTIISVYNQ DCVVDFIFHQ NGALEVKTSL TGYMMAMLHS LPEGRYGFQL
RDRLIGTVSQ HAFNFKVDLD IHETKNRYET LQFEPHSINN NDWSTEKNSR YEQIKFTRNS
KMTELHTLYR QNASVPMYHI FYNKGYKTTY NDPRAYRLQI DGGLTQLLSQ GTGNEPSISW
ARYQMAVTRR KDDEGQSSSI YAMWDKKEPI VNFQSFLDDN ESIVDTDLVA WVTLGLHHLP
QMEDLPLISS IGKRLSFFLT PFNYHDSDPS MASRDAIRMS YDGTSGTDQA VRVENYGLPK
DFTCDSEYQG GSESNYNLST LFEQN
//
