ID A0A210QJS6_MIZYE Unreviewed; 493 AA.
AC A0A210QJS6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Tyrosinase-like protein 2 {ECO:0000313|EMBL:OWF48969.1};
GN ORFNames=KP79_PYT16160 {ECO:0000313|EMBL:OWF48969.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF48969.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF48969.1}.
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DR EMBL; NEDP02003339; OWF48969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QJS6; -.
DR EnsemblMetazoa; XM_021500896.1; XP_021356571.1; LOC110452397.
DR OrthoDB; 70287at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..493
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012194204"
FT DOMAIN 204..221
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 338..349
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 493 AA; 56421 MW; E601AF21424A265D CRC64;
MKMKQTTTGF VFASIISSLL LNIVKVTGQH LLTSPATNCE QYRDHRGKFE ITGNDDSVHC
LQKHLYQFAL RSSPNDADNA YVDELLKKAL TRCSVKKSKA GLSKLSKKKC RSRKCKKMRY
KGRRGKRFAR KYYSNRERKY NAEQAGCNWE RKEVRMLSRP EWNQFTNRIN ILKRPIELPG
GGSFIPYDVI SNIHRVKTNL KAAHKGPNFL GWHRVYLLIM EAAIGVPIPY WDSRLDYDMD
EPVDSVLWTD EFFGPGIGRV DSGPFANWIT AHKEPLARNI GLSGSLISEC MVERMLRYKS
HDPVVDPTVR SISIEGIHNG PHRWVDGQLS IIRKASQDPV FFLHHSFIDY LWYLFRQLMR
ETGNINPATD YPDKGPKSQA RNENMIPFGN LRNIHGYSDI IEGLSRYKPP PKCPSCGGSD
YLECDRQINR CRSKASRTVA TLRDIQIRRR LAMDIVIRGT RFEGPVTDIR TSGVALGYLQ
LVNNTHLVNT GTL
//
