ID A0A210QMH6_MIZYE Unreviewed; 820 AA.
AC A0A210QMH6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|EMBL:OWF49937.1};
GN ORFNames=KP79_PYT04025 {ECO:0000313|EMBL:OWF49937.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF49937.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC {ECO:0000256|ARBA:ARBA00005241}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF49937.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NEDP02002897; OWF49937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QMH6; -.
DR STRING; 6573.A0A210QMH6; -.
DR EnsemblMetazoa; XM_021498935.1; XP_021354610.1; LOC110451080.
DR EnsemblMetazoa; XM_021498936.1; XP_021354611.1; LOC110451080.
DR OrthoDB; 5353125at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17335; MFS_MFSD6; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR16172:SF2; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6; 1.
DR PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 696..716
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..696
FT /note="Major facilitator superfamily associated"
FT /evidence="ECO:0000259|Pfam:PF12832"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 92271 MW; 38BA26BF42713FA9 CRC64;
MALELDSDDS DVGEGGRRGD CNKYKVRSQI NEGYNTSPKK RDIIDTFFTY VNRDLLICKL
FYFFFFAAFG SLFPLLAIYF KQLGMNPTQS GILIGFRPFV EFCSAPFWGS LADKYKKGKH
LMLFSLFCWI VFTLSIAFVK PPPHHCVETN ITYKLQSPPG YVSRDSVLRG RRSVLLGRKV
REEPFPALPK IRNDLDKRID MMNKSEGVPY NVPGKVPSGS KKPSDEYVKF QPLTAKPAVK
TTIQVKPTQK TQLSHAIPST ATMPHEATIT KPGASDSPKG SYIKPKYSTI YYEKHSVQDV
FFTLLLLVVI GEFFSAPAIT FADSVTLTYL GDDTDNYGRQ RMFGSLGWGF SMFFVGLALD
QSTTFPNHPC GLQHQAEKDY TICFAVFSVL MSCALFTATQ LKFDHRHGGG KDFQLVEFVE
KVKDRVMETI TGKRPLDRGS LFRDEEDDDI DYLESKATMQ KQMETGNAIN SCTEEDPNKL
QQPNGNGKNI QISLETRQDM VSDVTKKPVS ITGQEEDDDE PFLGRWIAVM RLLATYKYIT
VLFVSWFMGF GIGLIFTFLF WHLQDLGGSP TLFGVASVCN HISELLAYFL SRKLISRMGH
IRVMYAGLLG NVVRFMYISW LKSPWWVLPF EFVQGLTHAA VWAACCSYIT QAIPTGLRSS
AQGILQGLHH GLGRGCGAVF GGIMVYSYGA EVTFRAYGVT CLILLILYIV MNFFIVDHGK
FSFGSHEKHE ILEEEDNICH LAPHGVPSGM ARDLSSNKLR EEGMTNYGAT SYVPNGPGDD
FYPDNFDNDT QKITTNEPPA MATQVYQQQP YNTYDQRYGP
//
