ID A0A210QQY6_MIZYE Unreviewed; 373 AA.
AC A0A210QQY6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Toll-like receptor 3 {ECO:0000313|EMBL:OWF51141.1};
GN ORFNames=KP79_PYT25625 {ECO:0000313|EMBL:OWF51141.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF51141.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF51141.1}.
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DR EMBL; NEDP02002316; OWF51141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QQY6; -.
DR STRING; 6573.A0A210QQY6; -.
DR EnsemblMetazoa; XM_021496417.1; XP_021352092.1; LOC110449509.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR017241; Toll-like_receptor.
DR PANTHER; PTHR24365:SF541; MSTPROX-RELATED; 1.
DR PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:OWF51141.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 298..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 238..292
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 373 AA; 43257 MW; 3CA5944CC8E7BF13 CRC64;
MNLANNHFTK VPSFCGPTAQ LTGKYKTLKL QQNYIHDLDG SSFQCLQFLH NLFLDKNSVS
FIRSNTFAQL PKLEKLSMTF IGDHLETIEG YAFNSSSLKY LNIGNNRYKF DKRPWLYRTV
FASLPNLLSL ELTGNFLPSE SKALGELFTN LNKLEKLILE NTALKGLPRN VFQNIPNLES
LILIGNYISG WDDDPEVFGN VTSLRSLYLD GNNIKLVNKT SFPEHFLNSL DKLCLTNNPY
TCTCDLKWFL DWIKSTKHTI IVNYPRRYAC RYPPEMNNVL LKNYNPTTKI CSHIDYPLIR
NICIAVFVPS IIILIVVSVG YKFRFRLSYW LHILGIKRVG YKRIESDTDY RYDAFVIYSI
VNRDFVFNHM IPE
//
