ID A0A210QRU8_MIZYE Unreviewed; 1575 AA.
AC A0A210QRU8;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 {ECO:0000313|EMBL:OWF51465.1};
GN ORFNames=KP79_PYT04247 {ECO:0000313|EMBL:OWF51465.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF51465.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF51465.1}.
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DR EMBL; NEDP02002253; OWF51465.1; -; Genomic_DNA.
DR STRING; 6573.A0A210QRU8; -.
DR EnsemblMetazoa; XM_021495761.1; XP_021351436.1; LOC110449123.
DR OrthoDB; 5406861at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF2; SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR Pfam; PF02494; HYR; 2.
DR Pfam; PF00084; Sushi; 2.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00032; CCP; 6.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50825; HYR; 2.
DR PROSITE; PS50923; SUSHI; 3.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1575
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012577922"
FT TRANSMEM 1412..1438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 130..214
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 215..278
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 279..340
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 339..426
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 494..557
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 996..1031
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1033..1069
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 217..260
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1000..1010
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1021..1030
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1059..1068
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1575 AA; 171851 MW; 0C219667DE00976F CRC64;
MSGVGGYLPI LILATFLCQI LTVQGTVDGS CDISELPFDK LKCQDIKNDP VKPVNGAVSS
GHICVYKCSR NQQQTWAHCN NGQWNGEPEK CLENPSSIIH HRPRRWGRFF RRVFRAIKCV
FARCSKGPRG DSTPPKLTCP PDQNRNGDPF QTHAKATWVT PTALDSRDGT VTVYQSTSRR
SGFPISEPGA SIGFYAKDKS GNMAKCSFRI NVKVIRCPRL QRMTDGYAIC HRSDDMVLSS
YCRFGCYEGH ELIGPSYAQC KLTGRWSSWT LQQPSCRKHS CDPLLPSSPL LSITRTNGDL
FRSIATFSCV SGYDVPTGVR RAAVCGVDKT WSSTVPNCVD IEPPSFKPFP SSKTFYIARN
DNTVAVYWQG PEVEDNSGDT LAAEQKNTWP NQGDALAVGT YTVTYTATDS EGNIARPLNF
KITVKEIRCF HVYPTPYTSV ICTGNRLGST CRFNCSDGAK LNASSSVTSC DREGSPPYGV
WDWGTQQPFC ELPKNCQLPS APDNGALACD YWLGGRFCQP QCQVGYDISA RSTYTDLLIC
NDDGSHNWQL PLPNCMPSSS SGGTRRTVEV VFFTGSCSDE TTQIEIKQNF IKKLVSTSFS
HGCGSSPKCS WRNVQVICGN TNGKRSTGIT ISFEIAMNST AMNEEEYYNQ YMEYASLIET
LKVDVTSGTL TLQMNDNTTM KAAEMLMGDI GLQCVENTVA STKTFSCVEC QSGSYYDATT
EECVLCPVGQ YQTEPRKSTC IQCPYGTSTA TTGSSNQTQC QASCPPGSWS PSSLPPCTPC
DVGYYQSEFG ATGCIACPGN KITKIDNSSL EMECVDFDVY FPDNQTAGVL LSNKEAVPVI
GYTAVWWQQC SSDCTGEVFV LKNETGAKSL SMTFASTMTI SVEGQTISSG LAPPDDRGWH
VFTLKRKHTF LECFMDMSLL VNMTGLAEQT VIGGVTQLGG ISFEGTISQF NIFTESIPLA
TDKCSNDMSG DVISWRSILN ATMNDAFIQI PSVCDDVNEC DSSPCFRGNC TDDYNSYQCK
CEVGFTGNDC DVDLDDCEMN SCQNNATCQD SVNNYTCQCL PNFTGALCEI AMVDGDWNEY
SNWTECSVTC GNGTQIRFRA CDNPAPDNGG AECFGDSNET KVCEQESCPV CGELVPPING
SLKCINDGVD NVCELECDVG YVTDIPIPDN YSCGNSTFDQ WDFKLETNVF SRLPSCVETI
DPDDMRATRT SYYHGLDCNT LSTNTDTRIA VIGKLGAVVE SLTGVKNNDC KEDQKYINTC
ENRRRRDTSS ESAAYTIVLH CDSKSKGASE CYEILTQAVI GLESLEEQGE MNVVINGIEY
TINVSLSEAD TSLNCPTGMV EVLSYCVPCG PGRYYSEDEC ALCDFGFYQD ATQQTSCKAC
PTATSTEGTG SISAAECTVV LPVEDSVIDS SVLAVGVIAG IVAGVALFVL AVAICTAVRL
KKSKKKISDS TLFQRPSALH KGLTRESTTA SVMSITDIDS YYPTRTDTTA KTRWNSSSLK
DDDCMLEYQS PLFPKGHLIP PLTTEAPHLI HMTPLPDNQA PFFSRQQTQR IGSMPPITGQ
VDTSISTIDI LPIGN
//
