ID A0A210QTB9_MIZYE Unreviewed; 1188 AA.
AC A0A210QTB9;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Protocadherin Fat 4 {ECO:0000313|EMBL:OWF51983.1};
GN ORFNames=KP79_PYT06665 {ECO:0000313|EMBL:OWF51983.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF51983.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF51983.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NEDP02002011; OWF51983.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QTB9; -.
DR EnsemblMetazoa; XM_021494575.1; XP_021350250.1; LOC110448378.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 5.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR Pfam; PF00028; Cadherin; 2.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 5.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 823..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..218
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 219..330
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 331..435
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 528..617
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 631..726
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 892..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1160..1188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..978
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1188 AA; 132182 MW; 1EEACA819B37C172 CRC64;
MSHAAVQIFW LEPRLTRNSS SGIPIIDIPD SGVEKGDVFH TLNCSLVEIP AECKFFMDLR
RTDTNQTELY MKIDLLSNCN FDGKLCNNMQ CETGGPFSIL FRRIAENIHS IKFKHSSYTI
DVPESAVTGT ILYKFNASKM IDKTDCYSGT GGSGYVFSVK THNDTFGVSS STLHLKSKLD
YEKIETYNIT VSAVLYEQND TTEFIINVID VDDMDPHFID APYCLNITEN DTSTVNKYLS
TTPGIEAEDR DKGEGRQNLT YSIKSGSNGI FDIDNRNGCI QVHRLLFWKK DDPNVYHLTI
QATQDNDRDR YSTSGLTVYV IDTNNHRPKF STNPYYAVIG EHARVGAYVT KVHAEDDDEG
IFGETRYKLI NDNGLFMIDN QTGVIRVENS TGLDREQHPN ITLQVQSIDA EANETGSTTS
VEITLLDIND HTPQFSNDTY IFHINSSDTV HVHANDADIG GNGHISYKII RDNIPGVSIN
GDNGTIQFTN IHADIQFSVS ACDNPAISGS RRCSFVDVKA YLNGTTMGAY VKNMSVAENS
PVETVVGSMD IHEATFSIVE HHIPFNIKSD HLVRTTQVFD RENTSTYTFT VKVTGQINSD
VTVNVAVLDV NDNSPVFDKS EYVFGFPSGR SPVGNIRATD VDFDENGNVS YSFQHSFVAN
KYFDIDSRSG EITLSGVTIP SYQSSFQLGV LASDNGDPPM QSFCSVYISR VSVKGNYTVM
IATPLEEDDL KNMLSDLKSK IGNILNLTVN AQVSTAIHKR ATTTQVPRGI LEISAQYKNG
TKVLAKDLQR EVLLHLSEIE ALWAAEVNVP KKVSTDDSNL SQIALIVVAG VMLLATLIAV
IILSVKWREF KAREKILRLN DNLTRRSSLY ESQEIKVKMD DETSDYNGSL NTQDLESYDN
GHRPTGELNS FENPIYKGED LDETRVKAEA VNEALLSLND LSNRLEEEDP LAPKPDYEKS
EFENGSSLFQ NGDSELSDNV INGDLNTYDS MDSVKNTNNN QYENIEFGDD FPVTSGFAGL
KIDGKMISSS GEGHDDDVFI EENDDTDEKM TSDNDVIPEE EPDVDYHLKQ VRFANRVVNA
VTNVAEELKP DKSELVKDTG KEVDSKIDDD DSGDDNDDDD GKVFLVNEDS NNEYENEADF
RVDTTNASIR MDEEINSPLD FLKNDENNAD AGEDNGTFVF GEEECTSL
//
