ID A0A210QTT3_MIZYE Unreviewed; 774 AA.
AC A0A210QTT3;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|EMBL:OWF52173.1};
GN ORFNames=KP79_PYT10273 {ECO:0000313|EMBL:OWF52173.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF52173.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF52173.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NEDP02001917; OWF52173.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QTT3; -.
DR EnsemblMetazoa; XM_021494177.1; XP_021349852.1; LOC110448113.
DR OrthoDB; 2428249at2759; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 191..276
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 372..578
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 639..760
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
SQ SEQUENCE 774 AA; 86482 MW; 152489991178CAD3 CRC64;
MEYSTLEGSS GAHKKNLIKW KDACITGLVG LLIGLAIGLF IGNFDKKELG DGVFLPGISN
KIIQDGDPAV SDIIMDAIKS ENIREYLRDL TQLPHLAGTE ANYRLAMELH DFWRQEGLDE
VYVTPYDVLL SYPNVTDDDM MNRIELINAT GGVVYQSPLR EAILHPSENK SGVVPPFNAY
SAPGDITAER LVYVNYGRLE DYRWLRNNTS VNVTGAIVIA RYGQPFRGDK VKLATRYGAI
GIILYSDPAE DVPNGSTSKV YPDDWWLPPS GVQRGTVGKM SGDPLTRGYP ATETAYRYQQ
DSSEADLPTI PVHPVGYGTA EILLRELSGE EVPPQWKGGL NITYRLGGVL QTDGWTIRMF
ISTQSYMRRI HNVFGVIRGA IEPDRYVLIG NHRDAWVFGA IDPSSATAVM KEASRVMGNL
VKQGRWRPRR SIIFCSWDAE EYGLFGSYEW VEQYVKNLAA RSLAYINIDV AVTGNATFEP
IGTPLMHTIT YDATKKVVNP DSSESGEGIV TVYDKWLKRF PAPGTSRPLF RMAASQSDHA
PFIQLVGIPS VMLAFTGDSI PGANPLYHTR YDTFHILDEI IDRGFKTHRA VCQVTAEMAR
NLADSLTVPF NVSDLSEQLQ MRVTILDMEY GQLLRTHGIH FEWLQEAAEN FSSEVIKFQT
RADNINMNDP FAIRRINDQL ILLERAFIDP AGLPGRPLAR HVLFSHLDVN SYVGTTFPGL
VDSLLKLADA SEDETKALWE VIKQHFSVLV FTIQSAQTTL REVTTFMPDF QETV
//
