ID A0A210QV61_MIZYE Unreviewed; 531 AA.
AC A0A210QV61;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|EMBL:OWF52629.1};
GN ORFNames=KP79_PYT05854 {ECO:0000313|EMBL:OWF52629.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF52629.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}. Mitochondrion intermembrane
CC space {ECO:0000256|ARBA:ARBA00004569}.
CC -!- SIMILARITY: Belongs to the MICU1 family. MICU1 subfamily.
CC {ECO:0000256|ARBA:ARBA00038333}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF52629.1}.
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DR EMBL; NEDP02001725; OWF52629.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A210QV61; -.
DR STRING; 6573.A0A210QV61; -.
DR EnsemblMetazoa; XM_021493251.1; XP_021348926.1; LOC110447506.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006851; P:mitochondrial calcium ion transmembrane transport; IEA:InterPro.
DR CDD; cd15900; EFh_MICU; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039800; MICU1/2/3.
DR PANTHER; PTHR12294:SF1; CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12294; EF HAND DOMAIN FAMILY A1,A2-RELATED; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00022792};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022792};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 276..311
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 466..501
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 135..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 60985 MW; 2DF762677740AF95 CRC64;
MKPEALRWWV KAIGRPLSQS LSSKAGPSCR SFSSKQWQQT VYMQNKMILG RCGRNFAIRK
MLHSRGIAIT CSKCIQDGPY AYNKFGQGPD KENIGNKKNF GKACLGLLVG IASFILISNP
MSYLKTTVHA STGEVEKQDS GELLEAKEEG DEEEGAQTEK KKKKKIGFRD RRIIEYENRI
RAYSTPDKIF RYFATLKVHQ EQGDWEVYMT PEDFVRSITP GMKQPEGLGL DQFMKFDPQH
NKAEWKMGED SIFYQLGESG LISFSDYIFL LTVLSTPPRN FQIAFRMFDL DGDGNVDVEE
FRKVHQIIRN QTSIGMRHRD HAVTGNVMKG VSSALVTYFF GQEGKKKLTV PVFLTFQQQV
QNEVLRIEFD RYDPDDGKIT EKDFGRILLT YAGYPDKKKT RMLKRVIKKF KEEPQGITFE
EYTNFWRFLK SINDVDTALS FYHLAGVSID EETLKHVAKT VAHVHLTDHV VNVVFTLFDE
NNDGQLSNRE FVSVMKQRVM RGLEKPKDTG FIKLINATWK CTKSQTSAFL E
//
