ID   A0A210RY68_9BURK        Unreviewed;       348 AA.
AC   A0A210RY68;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Arsenical-resistance protein {ECO:0000313|EMBL:OWF65963.1};
GN   ORFNames=B6A14_09445 {ECO:0000313|EMBL:OWF65963.1};
OS   Polynucleobacter hirudinilacicola.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Polynucleobacter.
OX   NCBI_TaxID=1743166 {ECO:0000313|EMBL:OWF65963.1, ECO:0000313|Proteomes:UP000196880};
RN   [1] {ECO:0000313|EMBL:OWF65963.1, ECO:0000313|Proteomes:UP000196880}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MWH-EgelM1-30-B4 {ECO:0000313|EMBL:OWF65963.1,
RC   ECO:0000313|Proteomes:UP000196880};
RA   Hahn M.W.;
RT   "New species Polynucleobacter sp. MWH-EgelM1-30-B4.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWF65963.1}.
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DR   EMBL; NAIA01000003; OWF65963.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A210RY68; -.
DR   OrthoDB; 5290400at2; -.
DR   Proteomes; UP000196880; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        39..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        254..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        317..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   348 AA;  38459 MW;  99D2EB67FC8B8124 CRC64;
     MSSLTKKLSF LDRYLTVWIF AAMALGIGLG YFIPGVEGFI NSFQVGSTNY PIAIGLILMM
     YPPFAKVRYE DLPDVFRDKK IFAIAFLMNW IIAPVFMFLL AITFVPNQPE YMAGLILIGI
     APCIAMVIVW NDIAKGSTEY AAGLVAFNAI FQVLFFSLYA YIFLTVLPPH FGLAGSNISI
     TIGEIAKTVF IYLGIPCIAG LLTRFVMLKF VSKEWYHEHF VSQIGKLTLI ALLFTIVVMF
     SLKGKLILEL PGDVLTISIP LLIYFGVMFL LTFVITAKMG IDYKRCCTLS FTASSNNFEL
     AIAVAIAVFG INSGAAFAAV IGPLVEVPIM IGLVTVALWI KERYYKIA
//