ID A0A212EGN3_DANPL Unreviewed; 2219 AA.
AC A0A212EGN3;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Voltage-dependent T-type calcium channel subunit alpha-1H {ECO:0000313|EMBL:OWR40647.1};
GN ORFNames=KGM_205910 {ECO:0000313|EMBL:OWR40647.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR40647.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR40647.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR40647.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR40647.1}.
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DR EMBL; AGBW02015057; OWR40647.1; -; Genomic_DNA.
DR STRING; 278856.A0A212EGN3; -.
DR KEGG; dpl:KGM_205910; -.
DR eggNOG; KOG2302; Eukaryota.
DR InParanoid; A0A212EGN3; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 4.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR005445; VDCC_T_a1.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF230; CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR PRINTS; PR01629; TVDCCALPHA1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..790
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 810..825
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 845..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1402..1420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1440..1461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1473..1492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1537..1559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1640..1663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1720..1741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1753..1777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1783..1800
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1853..1873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1938..1964
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..314
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 654..878
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1401..1673
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1718..1973
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 933..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1089..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2012..2083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2097..2219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2097..2129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2158..2181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2182..2219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2219 AA; 250999 MW; 605ECFBC32C13DB5 CRC64;
MLIILLNCVT LGMYQPCVDD QCVTNRCKIL QVFDDIIFAF FTLELTIKMV AMGIYGHGTY
LADSWNRLDF FIVMAGALEY ALNVENINLS AIRTIRVLRP LRAINRIPSM RILVMLLLDT
LPMLGNVLLL CFFVFFIFGI VGVQLWEGIL RQRCELVLPP NVLRPNISFH YEFSKELDYI
CTTPEDSGMH LCGNFPPYRY GPLVCNDTAK PFSYNYPTNN SCVDWNQYYT NCTQRGPNPF
QGTISFDNIG LAWVAIFLVI SLEGWTDIMY YVQDAHSFWD WIYFVLLIVI GSFFMINLCL
VVIATQFSET KKREMERMRA ERARFTSSST LASSTNNSEP ATCYAEIVKY VAHLWRRFKR
RMAKKIRVYK YQRAQLKWRT SQETLQLPAN RPKQHHPCCP RVHVQGNGKG ITEEVGDEPL
SRPSLLRVPS LSAADLENAS NLSLLSPPSL ARRRSSVMFS DTVLLHVPNA QHLAHPHNVC
SSEKMTQTDS LCQRDWLKCQ SGESRMVDLD TLLERHALLN LLSLFFHFLE LLEFDLPPGE
TAEDRAAAGG TMSCQELLAL SGALSAALPT GQVALDTFFE ELTKGMSKRA GEDKMETKIV
EIEDFSCCAE LIAAEAAATE KKKGRIANAC IKLWRRILKF FSLLRKHIKT IVNHKYFQQG
ILLAILINTL SMGIEYHNQP QELTVIVEIS NVVFSGIFAV EMLLKIISEG PFNAFELAQS
MGNEHDLAGS SGLSVLRTFR LLRILKLVRF MPNLRRQLFV MLRTMDNVAV FFSLLVLFIF
IFSILGMNLF GCKFCKKDEE GDVECDRKNF DTLLWAFVTV FQVLTQEDWN VVLFNGMEKT
SHWAALYFVA LMTFGNYVLF NLLVAILVEG FSSERNERRE REQRELAKSK LSSECFSDNN
ELQYDESNSG SHSSDSFSQN EIKNYWKSAD DVRKVKDDNG HKDKSVKVRR KAKSSAHHPS
LCKDCAQSNK CNIQKESKML ASNIGTIENG NGTIVPKITH TAATPQDSPS TTLEPGATFR
DFNVALTLER STMLSSLDSI DRTSCTSIPG LLKPPNSYTL TLHSAAAQLG AEKARLPPPM
TLAPPPITLA PPPSRSTSPG SITPTIPRSL PSPIIPEKNF QVTIAKDENC LNVSDKSSLL
SSQKSLSITT PNIVGDDKYR VQRGYSWRLS RPSLRRKKQR TGSDSDAVVL NNGRDHIACN
GSNLRKNELL LSSTIVIKND TQSEINNRPK TQLPAPRVLA TQARRVSAHT TPILPDVSWK
APEVGAGFSS DSTVRLDAVK SPHHRLSLTN DYLTVTSGSE IKASNLAPAV APNAQIQSRN
EPVRTSSQAL PLIKQINEEV AINNSVCIFS SRFDRRRFHF KDLFRFMEPT GCLKEKEDYS
LYIFAPDNKI RTLCTWMVTR SAFDNIVLLF IALNCITLAM ERPNIPPDSK ERAFLSSANY
VFTVVFAVEM FIKVVASGMF YGSEAYFTSG WNIMDGSLVI ISIIDLLMSL VSESSPRIFG
ILRVFRLLRS LRPLRVINRA PGLKLVVQTL LSSLRPIGNI VLICCTFFII FGILGVQLFK
GAFFYCEGAS IKNVKNKSDC LAIEGNVWVN RKYNFDDLGK ALMSLFVLSS RDGWVNIMYT
GLDAVGVDQQ PIVNYSEWRL LYFIAFILLV GFFVLNMFVG VVVENFHRCR EEQEKEERVR
RAAKRALQME KKRRKMHQRP YYADYSQYRL FVHNVVTSKY FDLAIAGVIG LNVVTMAIEY
YRMPPALQYA LKIFNYFFTA VFILEAVMKL VALGFKIYLK DKWNQLDVII VILSIVGIVL
EELETNIIPI NPTIMRVMRV LRIARVLKLL KMAKGIRALL DTVMQALPQV GNLGLLFFLL
FFIFAALGVE LFGRLECSDE IPCQGLGEHA HFANFGMAFL TLFRVATGDN WNGIMKDTLR
EDCDSSVDCV RNCCVSTIIA PIFFVVFVLM AQFVLVNVVV AVLMKHLEES HKQMEDEIDM
DVELERELER EADDEEDRAL CRALEECVSP PRPLNKVPSL PANFTYSEPK QQPIPSPARR
RRTLHSHHAL LPAALPQRRA SLSPHAFGRR RQDSTPETPY PPALYEEEAR FIDADDIDEL
EPGSPPRHDS FSQNRRQRVD KRNSLRGEEA RLLRPAPILL AVPTTRQSLR RNSSKRRSST
ESGATSRLSQ MSVQTPSSPE ENNKEITEEE KIRIVIAERR KIDNIKPEPE DVELSERAS
//
