ID A0A212ELI2_DANPL Unreviewed; 135 AA.
AC A0A212ELI2;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Prefoldin subunit 4 {ECO:0000256|PIRNR:PIRNR016477};
GN Name=LOC116772730 {ECO:0000313|RefSeq:XP_032520892.1};
GN Synonyms=LOC116772731 {ECO:0000313|RefSeq:XP_032520893.1};
GN ORFNames=KGM_211632 {ECO:0000313|EMBL:OWR42345.1}, KGM_211633
GN {ECO:0000313|EMBL:OWR44092.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR42345.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR42345.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR42345.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR42345.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR42345.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032520892.1, ECO:0000313|RefSeq:XP_032520893.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC transfers target proteins to it. Binds to nascent polypeptide chain and
CC promotes folding in an environment in which there are many competing
CC pathways for nonnative proteins. {ECO:0000256|PIRNR:PIRNR016477}.
CC -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC subunits. {ECO:0000256|ARBA:ARBA00011695,
CC ECO:0000256|PIRNR:PIRNR016477}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000256|ARBA:ARBA00008045, ECO:0000256|PIRNR:PIRNR016477}.
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DR EMBL; AGBW02014056; OWR42345.1; -; Genomic_DNA.
DR EMBL; AGBW02013014; OWR44092.1; -; Genomic_DNA.
DR RefSeq; XP_032520892.1; XM_032665001.1.
DR RefSeq; XP_032520893.1; XM_032665002.1.
DR STRING; 278856.A0A212ELI2; -.
DR EnsemblMetazoa; XM_032665001.1; XP_032520892.1; LOC116772730.
DR EnsemblMetazoa; XM_032665002.1; XP_032520893.1; LOC116772731.
DR KEGG; dpl:KGM_211632; -.
DR KEGG; dpl:KGM_211633; -.
DR eggNOG; KOG1760; Eukaryota.
DR OrthoDB; 5476468at2759; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 18.
DR GO; GO:0016272; C:prefoldin complex; IEA:UniProtKB-UniRule.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.370; -; 1.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR016661; PFDN4.
DR InterPro; IPR009053; Prefoldin.
DR PANTHER; PTHR21100; PREFOLDIN SUBUNIT 4; 1.
DR PANTHER; PTHR21100:SF9; PREFOLDIN SUBUNIT 4; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR PIRSF; PIRSF016477; Prefoldin_subunit_4; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR016477};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151}.
FT COILED 28..119
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 135 AA; 15352 MW; CF80FFEF09EC6248 CRC64;
MANSGKGTFQ RDSDVHISYE DQQKINKFAR LNAKVDDLKD ELKVKQNDMK NLEEAVEELG
LADDSEKIPY LVGEVFICQS LEDTLQSLED NKTKKQDEIA ELEAKCDDLK SQMAELKAHL
YGKFGSHINL ENEES
//
