ID A0A212ELM0_DANPL Unreviewed; 984 AA.
AC A0A212ELM0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Uncharacterized protein LOC116779066 isoform X2 {ECO:0000313|RefSeq:XP_032529108.1};
GN Name=LOC116779066 {ECO:0000313|RefSeq:XP_032529108.1};
GN ORFNames=KGM_215769 {ECO:0000313|EMBL:OWR42361.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR42361.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR42361.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR42361.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR42361.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR42361.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032529108.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; AGBW02014037; OWR42361.1; -; Genomic_DNA.
DR RefSeq; XP_032529108.1; XM_032673217.1.
DR STRING; 278856.A0A212ELM0; -.
DR EnsemblMetazoa; XM_032673217.1; XP_032529108.1; LOC116779066.
DR KEGG; dpl:KGM_215769; -.
DR eggNOG; KOG1215; Eukaryota.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 4.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07066; CRD_FZ; 1.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270:SF66; CUB AND LDLA DOMAIN, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR Pfam; PF01392; Fz; 1.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00063; FRI; 1.
DR SMART; SM00192; LDLa; 3.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR PROSITE; PS50038; FZ; 1.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 216..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 504..615
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT REGION 18..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 819..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 552..590
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 619..631
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 626..644
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 638..653
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 656..668
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 663..681
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 948..960
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 955..973
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 967..982
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 984 AA; 109641 MW; 0D97880700473667 CRC64;
MVNGNYVLYG DRPASESQIV SDHVQTRTAE RKPKRKSNRT ANEVQHTLNL DELDNQTDTV
KYENKIKEPK LLRYVPTTEV EENFVTERFE TLDAKMNDEP PRRNFTKKPK NPSDGSVNYA
YSRSSSSCSS PNGNLPTISE HVEQYGTYRV CSPHSPPRSM SNINCYESKL DKYFSKPRDL
KTFTAKGSHP DSLYRVSSDE AAGSDRLMRA LRLLRWPLAL FTVCVALAAF VYFLMPVNMD
SEIDAVNGTF WEESVSEAQS HSAPKISKNL NEERKTRPLG KTPEIDFYDA DNGNVNDLGS
IVDTMASPNR KLPAPPVFPS HVSLEVQYGN EKADSDKARM SKVLKEPEDE STLKPHITQK
PEKPLAIYFK DANSITTSTD AGLIAETFTD AESSNDIAIF LKKQPNKLAD QNKLHQTNPS
LFNKNDIKTR FVAPEVSEYY ARPAANSEVK FTSGHSKFFG ISIEDAQNMK STTQNSLYNT
RVSPTLPTWK DRGDATTKKY PINYDAPQCR STRLSLCRGV LPYDLASAPA SIAMTDVTTL
LPQIEYLVST NCSERVRHFA CSLLEPECSP PPYSPKLPCY NFCKAIVDSC EGNIPSELQP
MFSCNQYSTG NCAPARGPCY QRELACGDGT CVPRDWVCDG TRDCPAGEDE APCSACDDNE
YRCSSGMCIT KRWLCDGYAD CASGEDERDE LCRGRLRNGL LRDRNQKLAG RYDGGGAEDT
HEPGEELAGS APAPSVRKPN RLPVDGRNGE NESSKELLMT SDSNSGFRRN FTRRPSPSRL
TPYKRLQAMT PLQDKTSSEE EKELLFMETS LRNKTNKTNK TNTTKEPDNK KDSAEDLTLD
DLGLFDIEKN KPVEVNMDNK TETHAQRANA QEAAVHKQDS VEEPTHTSVA VRVNQTMKKL
DRVIDGASML RKAAKERQAD IMESIESNGT AVDNSEDMAY NSAHASPCPS SELRCVDGRC
ITLSQLCDGT IDCSDHADED NCYT
//
