ID A0A212EU78_DANPL Unreviewed; 562 AA.
AC A0A212EU78;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Signal transducer and activator of transcription short form {ECO:0000313|EMBL:OWR45050.1};
DE Flags: Fragment;
GN ORFNames=KGM_212956A {ECO:0000313|EMBL:OWR45050.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR45050.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR45050.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR45050.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC {ECO:0000256|ARBA:ARBA00005586}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR45050.1}.
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DR EMBL; AGBW02012449; OWR45050.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A212EU78; -.
DR STRING; 278856.A0A212EU78; -.
DR KEGG; dpl:KGM_212956A; -.
DR eggNOG; KOG3667; Eukaryota.
DR InParanoid; A0A212EU78; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd16855; STAT5_CCD; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.20.1050.20; STAT transcription factor, all-alpha domain; 1.
DR Gene3D; 2.60.40.630; STAT transcription factor, DNA-binding domain; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001217; STAT.
DR InterPro; IPR046994; STAT5_CCD.
DR InterPro; IPR048988; STAT_linker.
DR InterPro; IPR013800; STAT_TF_alpha.
DR InterPro; IPR015988; STAT_TF_coiled-coil.
DR InterPro; IPR013801; STAT_TF_DNA-bd.
DR InterPro; IPR012345; STAT_TF_DNA-bd_N.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF43; SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR; 1.
DR Pfam; PF01017; STAT_alpha; 1.
DR Pfam; PF02864; STAT_bind; 1.
DR Pfam; PF21354; STAT_linker; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF47655; STAT; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..173
FT /note="STAT transcription factor all-alpha"
FT /evidence="ECO:0000259|Pfam:PF01017"
FT DOMAIN 185..323
FT /note="STAT transcription factor DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF02864"
FT DOMAIN 346..432
FT /note="Signal transducer and activator of transcription
FT linker"
FT /evidence="ECO:0000259|Pfam:PF21354"
FT COILED 47..74
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 562
FT /evidence="ECO:0000313|EMBL:OWR45050.1"
SQ SEQUENCE 562 AA; 64190 MW; 467712F4C926A348 CRC64;
MASEEIRSLQ ANIESFSLQY HECLKNKGHI NYLQQSGPMT NDRRELEACL RVQIEDMERK
LNALVAQINQ SQMELVDHMK ENITNLRQLQ SQVLDEELIK WKREQQLSGN GVPMQSNLNS
IQEWCELLAE LIWSTRQQVC NVGRINSKTI VELRQPHLAE MLDDMSKQVT SLLSTLVTST
FVIEKQPPQV MKTNTRFTAT VRLLVGGQLN VHMTPPRVTV VIISEQQAQL LLKSDVSGGR
GKQPQECGDI LNNSGCMEYQ PTCRQLSVSF RNMQLRKIKR AEKKGTESVM DEKLTLLFQS
EFNVGGGELV FQVWTLSLPV VVIVHGNQEP HGWATVTWDN AFSPPGRVPF AVPDKVTWGQ
LAETLRIKFC SATGGDLSED NLRFLAEKIF SSHVDRTSLP LTALELNNMS VSWTQFCKDA
LPDRNFTFWE WFYMVVKVTR DYLRTLWCDR RSMRMDCGLT HQPNKLRGEG NEVFSLQPFT
SRDLMLRSLA DRILDLAQLQ FLYPNVAKDD VFSKYYTKPE NEMLKNGYVK PVLVTTLPPY
MSASPAYAHS PDSHRNTPSV HS
//
