ID   A0A212EVP0_DANPL        Unreviewed;       940 AA.
AC   A0A212EVP0;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
GN   ORFNames=KGM_209236 {ECO:0000313|EMBL:OWR45556.1};
OS   Danaus plexippus plexippus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX   NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR45556.1, ECO:0000313|Proteomes:UP000007151};
RN   [1] {ECO:0000313|EMBL:OWR45556.1, ECO:0000313|Proteomes:UP000007151}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F-2 {ECO:0000313|EMBL:OWR45556.1};
RX   PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA   Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT   "The monarch butterfly genome yields insights into long-distance
RT   migration.";
RL   Cell 147:1171-1185(2011).
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWR45556.1}.
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DR   EMBL; AGBW02012158; OWR45556.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212EVP0; -.
DR   STRING; 278856.A0A212EVP0; -.
DR   KEGG; dpl:KGM_209236; -.
DR   eggNOG; KOG1052; Eukaryota.
DR   InParanoid; A0A212EVP0; -.
DR   Proteomes; UP000007151; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR   PANTHER; PTHR42643:SF13; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        517..545
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        597..619
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          525..798
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00060"
SQ   SEQUENCE   940 AA;  107094 MW;  6D7AD191D23FD034 CRC64;
     METVVLDHQF LGDEYQMMLE DLEDYIKELV RVELKHGGIN VHYYSWTSIN LKKGFLAIFS
     IASCEDTWSL FLRAEEEDLL HIAVTEVDCP RLPSDSAITV TFADPGQELP QLVLDLRTRK
     AFNWKSAIIL HDETLNRDMV SRVVESLTSQ IDDISSISVS VYKMRHENNE YLRRKEVYRV
     LKKLPVKYIG ENFIAIVTTD VMATIAEIAR ELRMSHTQAQ WLYLVPDTDS HTGNVTNLIN
     DLYEGENIAY IFNFTDDRGC KNGLKCYAHE VLDSFISALE AAVLDELEAA LQVSDEEWEA
     VRPTKLQRRN SLLWHMQQYL STRSVCGNCS SWRALSADTW GATYDRADEN TSSLIEQVHL
     VQVGFWRPID GVTFEDVLFP HIQHGFRGKQ LPIMTYHSPP WTIVTYNASG AVTSYGGLLF
     DIVNQLAKNK NFTYAIYILL LAENLRLNYT NETTTDTLYN TNRQLILSAI AKGHAALVAA
     PFTVSPDTHP GVNFTVPVST QSYSFIIARP RELNRALLFL LPFTTDTWLC IAFAVVLMGP
     TLYVVHRVSP YYEAMEITRE GGLSTIYNCL WYIYGALLQQ GGMYLPRADS GRLVVGTWWL
     VVLVVVTTYS GNLVVFLTFP KLEIPVTTVS ELLDSGTYSW SIRSGSFLES QLKNSNEPKY
     EALLKRAELT SPSDGAENDA IVERVRFSHH ALFDWKLRLR YLMRADTEQT DSCDFALSTE
     EFMDEQVAMI LPAGSPYLPV INKEINRMKK AGLITKWLSA YLPKRDRCWK TSAITQEVNN
     HTVNLSDMQG SFLVLFLAIV ERVRFSHHAL FDWKLRLRYL MRADTEQTDS CDFALSTEEF
     MDEQVAMILP AGSPYLPVIN KEINRMKKAG LITKWLSAYL PKRDRCWKTS AITQEVNNHT
     VNLSDMQGSF LVLFLDSQKT CAPEKAVVEL TPGTVWSTRY
//