ID A0A212EYT2_DANPL Unreviewed; 519 AA.
AC A0A212EYT2;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Fatty-acid amide hydrolase 2-A-like {ECO:0000313|RefSeq:XP_032512779.1, ECO:0000313|RefSeq:XP_032512780.1};
DE SubName: Full=Putative amidase isoform 1 {ECO:0000313|EMBL:OWR46659.1};
GN Name=LOC116766790 {ECO:0000313|RefSeq:XP_032512779.1,
GN ECO:0000313|RefSeq:XP_032512780.1, ECO:0000313|RefSeq:XP_032512781.1,
GN ECO:0000313|RefSeq:XP_032512784.1};
GN ORFNames=KGM_201225 {ECO:0000313|EMBL:OWR46659.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR46659.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR46659.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR46659.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR46659.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR46659.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032512779.1, ECO:0000313|RefSeq:XP_032512780.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGBW02011440; OWR46659.1; -; Genomic_DNA.
DR RefSeq; XP_032512779.1; XM_032656888.1.
DR RefSeq; XP_032512780.1; XM_032656889.1.
DR RefSeq; XP_032512781.1; XM_032656890.1.
DR RefSeq; XP_032512784.1; XM_032656893.1.
DR STRING; 278856.A0A212EYT2; -.
DR EnsemblMetazoa; XM_032656888.1; XP_032512779.1; LOC116766790.
DR EnsemblMetazoa; XM_032656889.1; XP_032512780.1; LOC116766790.
DR EnsemblMetazoa; XM_032656890.1; XP_032512781.1; LOC116766790.
DR EnsemblMetazoa; XM_032656893.1; XP_032512784.1; LOC116766790.
DR KEGG; dpl:KGM_201225; -.
DR eggNOG; KOG1212; Eukaryota.
DR OrthoDB; 146362at2759; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR PANTHER; PTHR43372:SF3; AT07710P-RELATED; 1.
DR PANTHER; PTHR43372; FATTY-ACID AMIDE HYDROLASE; 1.
DR Pfam; PF01425; Amidase; 1.
DR PIRSF; PIRSF001221; Amidase_fungi; 2.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|RefSeq:XP_032512779.1,
KW ECO:0000313|RefSeq:XP_032512780.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..503
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
FT ACT_SITE 125
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 200
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 224
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
SQ SEQUENCE 519 AA; 56237 MW; D9AF1A0EB5CB8CD8 CRC64;
MEVGVWIVGV LLRVLCFITA PFFWLRTRKE QRVPPIKDPL LMKSATKLAA EIRNGELTSE
NLVSRYVLRI QEVNPYINAV VEDRFQAAME EARDVDRKIS EARGRGDLDK LVADKPLLGV
PFTVKESCSL AGMSNSVGCL EFLGRRALTD GGGVSRVRAA GGIPLLVSAT PELCLGWETT
SLLRGHTNNP YGLARTPGGS SGGEAALVSS GASVISVSSD IAGSIRIPAA FCGLYGHKPT
PGIIPISGHI PTLQDEQYAR FLTVGPITRY SEDLPLMMKV LAGDRAHELD LDTPVALHEL
KVYFMTEASR SVAFSPVELS IQRAILAAVQ HLKSRGATVC EDKFNDFEDA VEMSASVFFS
MKDIPNMLQD PANPKREKNL ILETLKTLLG SGSRTLQALG FEVLKRKRLF VPKEKVPHYI
ERTDRLRETM ERALGCSGVF LFPSHSCSCH AHGGVFVKAA GVVYTMPFNA LGLPATSVPI
PGPGPRPVAV QVVAGPGQDR LCLAVARELE NKFGGWTPP
//
