ID   A0A212EZJ5_DANPL        Unreviewed;       998 AA.
AC   A0A212EZJ5;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Folliculin-interacting protein 2 isoform X2 {ECO:0000313|RefSeq:XP_032510820.1};
GN   Name=LOC116765480 {ECO:0000313|RefSeq:XP_032510820.1};
GN   ORFNames=KGM_210130 {ECO:0000313|EMBL:OWR46925.1};
OS   Danaus plexippus plexippus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX   NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR46925.1, ECO:0000313|Proteomes:UP000007151};
RN   [1] {ECO:0000313|EMBL:OWR46925.1, ECO:0000313|Proteomes:UP000007151}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F-2 {ECO:0000313|EMBL:OWR46925.1};
RX   PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA   Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT   "The monarch butterfly genome yields insights into long-distance
RT   migration.";
RL   Cell 147:1171-1185(2011).
RN   [2] {ECO:0000313|EMBL:OWR46925.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=F-2 {ECO:0000313|EMBL:OWR46925.1};
RA   Zhan S., Reppert S.M.;
RT   "MonarchBase: the monarch butterfly genome database.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:XP_032510820.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00004656}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004370}.
CC   -!- SIMILARITY: Belongs to the FNIP family.
CC       {ECO:0000256|ARBA:ARBA00007541}.
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DR   EMBL; AGBW02011262; OWR46925.1; -; Genomic_DNA.
DR   RefSeq; XP_032510820.1; XM_032654929.1.
DR   STRING; 278856.A0A212EZJ5; -.
DR   EnsemblMetazoa; XM_032654929.1; XP_032510820.1; LOC116765480.
DR   KEGG; dpl:KGM_210130; -.
DR   eggNOG; KOG3693; Eukaryota.
DR   Proteomes; UP000007151; Unassembled WGS sequence.
DR   Proteomes; UP000596680; Chromosome 6.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR037545; DENN_FNIP1/2.
DR   InterPro; IPR028086; FNIP_C_dom.
DR   InterPro; IPR026156; FNIP_fam.
DR   InterPro; IPR028085; FNIP_mid_dom.
DR   InterPro; IPR028084; FNIP_N_dom.
DR   PANTHER; PTHR21634:SF9; RE13835P; 1.
DR   PANTHER; PTHR21634; UNCHARACTERIZED; 1.
DR   Pfam; PF14638; FNIP_C; 1.
DR   Pfam; PF14637; FNIP_M; 1.
DR   Pfam; PF14636; FNIP_N; 1.
DR   PRINTS; PR02073; FOLLICULNIP1.
DR   PROSITE; PS51836; DENN_FNIP12; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007151}.
FT   DOMAIN          29..985
FT                   /note="UDENN FNIP1/2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51836"
FT   REGION          612..660
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        622..646
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   998 AA;  111620 MW;  F42373B0B1705107 CRC64;
     MALIENIFRR RKIDYAYWDS RIRGRAGELA LEQVRLLLYK ECDRRGRKVL FDSSTIDKVL
     SAKNDRPDIK MEKIPCIVEV TDGNSYIYKG QATDASVLGE MIFGAVAMNC KSVSFKIHIM
     NEPKRLMCTK LFSVPVSRKT SRMERKADSC SGDVNRSRPL NMTLLREEGL ALSFSLDRGD
     SGFCETSSYS SFGTSFDYLT MFHDWDQNGD EHYFYSPSSK LSASSGSLAR RTSHSYATRF
     DFGNTLKVPT SSTVCSADSQ LYSSSTSTSD SLASTASTRR AKLGLALLIT FTESDDMELI
     RRCLELSPQL RSLVCRLRLA ALTAGSDAFF VSTLHTAAGH ARRWLSELLF GPRLHPTWLL
     LVSSEPSQAN KMADRLIEDI CSVLAIGDTK DTNFFISTLL THVLTHHLGW VTTVSPYDRV
     ESKNTGNLDT KRPYNALWAQ LTDLCGCIGF PPKSARTIIT GNKNILFINR LLDVLTYFIR
     CGDVKKNDFV YRDCSVSEVK VINVKAASEN DKCDLNDYST KYSLKVPSYS GSSASTLVSS
     EVSLKKSATF VDLNNVLSNF DFASDNGSKL RRHPTMMISL KDSDSSSNAS SEECEKNVVF
     VLGDDEKLVG LKNKSNGKRN LKKTSRASET EEKEKEERDD VSQEKYKSSQ SPKCCDQTLK
     HSKPIKHSGF KFEFDKYPQI VTNYMKSKNL EILDRHYIGK PGNLKLDNFQ FDPTFVPPIQ
     EDRCETCYKC QLMESMLQTP TNASEMEYMN DIPRQSEPQI AKETIVQEEM TPKTFVRKRK
     ESTVVVNVRK PVTEVKVKVD EEKDNNVIEV KQVLEFPVPQ VCPIAKTDCN DTLLGGITDH
     YVPDLILQGT IANPDTWESE LRRDLDLTSY LNKSSDSPIQ TVAIVGDTNT WQVRVCGRSV
     GPMGGGLSPL VGGILDALPA MRKANVPAAQ CLLFLESKLR EFCVLSKTLA DILMSTDFCD
     IATLTKSLNV DVNDVPLLLA VATTHTPELA TRYGISYR
//