ID   A0A212F5Q3_DANPL        Unreviewed;       313 AA.
AC   A0A212F5Q3;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Phosphopantothenate--cysteine ligase {ECO:0000313|RefSeq:XP_032515779.1, ECO:0000313|RefSeq:XP_032515780.1};
DE   SubName: Full=Phosphopantothenoylcysteine synthetase isoform A {ECO:0000313|EMBL:OWR49058.1};
GN   Name=LOC116768954 {ECO:0000313|RefSeq:XP_032515779.1,
GN   ECO:0000313|RefSeq:XP_032515780.1};
GN   ORFNames=KGM_210635 {ECO:0000313|EMBL:OWR49058.1};
OS   Danaus plexippus plexippus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX   NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR49058.1, ECO:0000313|Proteomes:UP000007151};
RN   [1] {ECO:0000313|EMBL:OWR49058.1, ECO:0000313|Proteomes:UP000007151}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F-2 {ECO:0000313|EMBL:OWR49058.1};
RX   PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA   Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT   "The monarch butterfly genome yields insights into long-distance
RT   migration.";
RL   Cell 147:1171-1185(2011).
RN   [2] {ECO:0000313|EMBL:OWR49058.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=F-2 {ECO:0000313|EMBL:OWR49058.1};
RA   Zhan S., Reppert S.M.;
RT   "MonarchBase: the monarch butterfly genome database.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:XP_032515779.1, ECO:0000313|RefSeq:XP_032515780.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PPC synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005703}.
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DR   EMBL; AGBW02010155; OWR49058.1; -; Genomic_DNA.
DR   RefSeq; XP_032515779.1; XM_032659888.1.
DR   RefSeq; XP_032515780.1; XM_032659889.1.
DR   STRING; 278856.A0A212F5Q3; -.
DR   KEGG; dpl:KGM_210635; -.
DR   eggNOG; KOG2728; Eukaryota.
DR   OrthoDB; 6287at2759; -.
DR   Proteomes; UP000007151; Unassembled WGS sequence.
DR   Proteomes; UP000596680; Chromosome 12.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.10300; CoaB-like; 1.
DR   InterPro; IPR035929; CoaB-like_sf.
DR   InterPro; IPR007085; DNA/pantothenate-metab_flavo_C.
DR   PANTHER; PTHR12290; CORNICHON-RELATED; 1.
DR   PANTHER; PTHR12290:SF2; PHOSPHOPANTOTHENATE--CYSTEINE LIGASE; 1.
DR   Pfam; PF04127; DFP; 2.
DR   SUPFAM; SSF102645; CoaB-like; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000313|RefSeq:XP_032515779.1,
KW   ECO:0000313|RefSeq:XP_032515780.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007151}.
FT   DOMAIN          38..95
FT                   /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
FT   DOMAIN          167..265
FT                   /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
SQ   SEQUENCE   313 AA;  35062 MW;  0C0C63C5B28570F9 CRC64;
     MASGSWEEFF AVHLPPTDFE DNRSLLKEFC ERHDQYGNKI VLVTSGGTTV PLEHNTVRFV
     DNFSAGTRGS ASAEYFLEHG YAVIFMHRQK SLEPFTRHFT GQKLLDMLDL QERGPNTTIT
     VKPDSVFALA PVLARYQAAH AAGALLHVSF TTVSEYFWLL RAACECLAHT GARAVLYLAA
     AVSDFYIPKD RVPTHKMQSA SGAPVIQLHL VPKMLAPLVN LWVPEAYVVS FKLETDENLL
     IPKARAALEK YKHKMVVANL LQTRHHRVIL VTSNAVQEIL LTREEVHAGV DIESMIVGEL
     VRQHAEHMSA RPR
//