ID A0A212F6N4_DANPL Unreviewed; 1054 AA.
AC A0A212F6N4;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Putative Diaphanous {ECO:0000313|EMBL:OWR49401.1};
DE Flags: Fragment;
GN ORFNames=KGM_203186B {ECO:0000313|EMBL:OWR49401.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR49401.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR49401.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR49401.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
CC -!- SIMILARITY: Belongs to the formin homology family. Diaphanous
CC subfamily. {ECO:0000256|ARBA:ARBA00008214}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR49401.1}.
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DR EMBL; AGBW02009985; OWR49401.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A212F6N4; -.
DR STRING; 278856.A0A212F6N4; -.
DR KEGG; dpl:KGM_203186B; -.
DR eggNOG; KOG1924; Eukaryota.
DR InParanoid; A0A212F6N4; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.630; -; 1.
DR Gene3D; 6.10.30.30; -; 1.
DR Gene3D; 1.10.20.40; Formin, diaphanous GTPase-binding domain; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR044933; DIA_GBD_sf.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR PANTHER; PTHR45691:SF6; PROTEIN DIAPHANOUS; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151}.
FT DOMAIN 126..513
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 581..980
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 999..1028
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 500..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1016..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 444..478
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 504..571
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1039
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OWR49401.1"
SQ SEQUENCE 1054 AA; 118193 MW; 69D8252AD54D16B4 CRC64;
SGYATSMFIS AQKHITLPKN KITLKNIVKL SERTKPRAQL ADNGFDPIYK SVSIVLNLDV
TSIVLYYITV DKKGGVVWLT WKKELDTWFG RPKKTGGGID RGYDTVPRAE LRPDDEEPAT
EYTAKIDALD DDQLERRFEE MLTDMNIGEK KKEPLRKYSR DQKKKMLVAY KFVNAQEGRS
KFEKPADYVS YLNQPELSVG KLHSCLENLR ISLTNNPLSW IEEFGPKGIE SLLTTLNVCY
TNDSRYDRVQ YECIRCLSAI LNNTVGIRAV FDCREALPVL ARSLDARKPH CALEAAKVLA
AICLIPNGHE KVLEAITMAG ESSRRPRLLP IIEGLSPKAP ESLKNGCISI ILTWVDFHDV
NECFELVKNL VVETPAEPYL LSILQHLLFI RDDELIRPAY YKLIEECVTQ IVLHKNGYDP
DFRLTQRFNI DVQPLIEGLI EKSRAEEERK VEELKSKLEA AIAARQEAEA RVAHLEQRLK
TAPPSGPGGV TQGNIAAIAK AIGSPGGPPP PPPPPMPGGG PPPPPPPPMP GAGAPPPPPP
PIPGGPPPPP MPGGPRPPPP PGMPSAPRMP QPDVLPHGLK PKKKWEVEGP LKRANWKTIV
PQKMSEKAFW LKVQEDKLAS PDILTGLAQK FSSKPMAKKN EDNVDRAHTL KKAKDLKVLD
SKAAQNLSIL LGGSLKHLSY EHIKTCILRC DTTVLNANVL DLLIQYLPPA DQLRKLSDLR
CSSDELTEAE QFAAVVSDVK RLAPRLRSLA FREHYQEIVS ELKPDIVSGT AACEEVRSSV
KFARILELLL LLGNYMNTGS NNAGAYGFEI SFITKLTATK DLENKQTLLH YLVNTIETKF
PEVLNFAEEM PHIDRAARVS PENLQKALKK MENDIRSLET DLNNSRVPQC ADDLFHETMS
NFAKEAREQC DLLHSMFKKM ESLYAELAEY YVFDPAKYTL EEFFADVKTF KDSFATAHQE
NVIARETEER ARRARDARAA AERDRRDRQM RYKQFVDMER AQDGVMDSLM EALQSGSAFS
RERPRKKANP RVAGEDSDEE RELVRAILSR IEGK
//
